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Database: UniProt
Entry: I4EB71_METSZ
LinkDB: I4EB71_METSZ
Original site: I4EB71_METSZ 
ID   I4EB71_METSZ            Unreviewed;       142 AA.
AC   I4EB71;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Transcriptional regulator, MerR family protein {ECO:0000313|EMBL:CCD32227.1};
GN   Name=merR {ECO:0000313|EMBL:CCD32227.1};
GN   OrderedLocusNames=SC2p2_00710 {ECO:0000313|EMBL:CCD32227.1};
OS   Methylocystis sp. (strain SC2).
OG   Plasmid pBSC2-2 {ECO:0000313|Proteomes:UP000005263}.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylocystaceae; Methylocystis.
OX   NCBI_TaxID=187303 {ECO:0000313|EMBL:CCD32227.1, ECO:0000313|Proteomes:UP000005263};
RN   [1] {ECO:0000313|Proteomes:UP000005263}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC2 {ECO:0000313|Proteomes:UP000005263};
RC   PLASMID=pBSC2-2 {ECO:0000313|Proteomes:UP000005263};
RX   PubMed=23045511; DOI=10.1128/JB.01446-12;
RA   Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT   "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT   Methanotroph with High-Affinity Methane Oxidation Potential.";
RL   J. Bacteriol. 194:6008-6009(2012).
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DR   EMBL; FO000002; CCD32227.1; -; Genomic_DNA.
DR   AlphaFoldDB; I4EB71; -.
DR   Proteomes; UP000005263; Plasmid pBSC2-2.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd04785; HTH_CadR-PbrR-like; 1.
DR   Gene3D; 1.10.1660.10; -; 1.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   InterPro; IPR047057; MerR_fam.
DR   InterPro; IPR015358; Tscrpt_reg_MerR_DNA-bd.
DR   PANTHER; PTHR30204:SF93; HTH-TYPE TRANSCRIPTIONAL REGULATOR ZNTR; 1.
DR   PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR   Pfam; PF00376; MerR; 1.
DR   Pfam; PF09278; MerR-DNA-bind; 1.
DR   PRINTS; PR00040; HTHMERR.
DR   SMART; SM00422; HTH_MERR; 1.
DR   SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR   PROSITE; PS50937; HTH_MERR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          9..78
FT                   /note="HTH merR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50937"
SQ   SEQUENCE   142 AA;  15391 MW;  D096F6563BEA3A04 CRC64;
     MQEKKSMQPL TIGRLAAAAC VNFETVRYYE RIGLMPPPAR TEGGHRAYEA AHVRRLTFIR
     RARELGFSIG DIRALLALAE PSHASCAQAQ EIAQAHLDDV RAKLADLAKL ERILAGTVVR
     CSGDPAPSCP VLDMLDAGVK LG
//
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