ID I4EW69_9ACTN Unreviewed; 362 AA.
AC I4EW69;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:CCH87632.1};
GN OrderedLocusNames=MODMU_2197 {ECO:0000313|EMBL:CCH87632.1};
OS Modestobacter marinus.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Modestobacter.
OX NCBI_TaxID=477641 {ECO:0000313|EMBL:CCH87632.1, ECO:0000313|Proteomes:UP000006461};
RN [1] {ECO:0000313|EMBL:CCH87632.1, ECO:0000313|Proteomes:UP000006461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC501 {ECO:0000313|EMBL:CCH87632.1,
RC ECO:0000313|Proteomes:UP000006461};
RX PubMed=22887672; DOI=10.1128/JB.01029-12;
RA Normand P., Gury J., Pujic P., Chouaia B., Crotti E., Brusetti L.,
RA Daffonchio D., Vacherie B., Barbe V., Medigue C., Calteau A.,
RA Ghodhbane-Gtari F., Essoussi I., Nouioui I., Abbassi-Ghozzi I., Gtari M.;
RT "Genome Sequence of Radiation-Resistant Modestobacter marinus Strain BC501,
RT a Representative Actinobacterium That Thrives on Calcareous Stone
RT Surfaces.";
RL J. Bacteriol. 194:4773-4774(2012).
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DR EMBL; FO203431; CCH87632.1; -; Genomic_DNA.
DR RefSeq; WP_014740226.1; NC_017955.1.
DR AlphaFoldDB; I4EW69; -.
DR STRING; 477641.MODMU_2197; -.
DR KEGG; mmar:MODMU_2197; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_11; -.
DR OMA; VAADHWQ; -.
DR OrthoDB; 3258243at2; -.
DR Proteomes; UP000006461; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006461};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..63
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 328..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 37030 MW; 0A4BBC0F7046281F CRC64;
MDGERARDVT IYDVARAAGV AASTVSRTFS RPGRVNAATA ERVRQVADTL GYRTNPLARA
LSTARTHMLA VLVSDIGNPV YGEMVRGVQS VATQAGYTVL LADSQESDRT ERAALERALP
SVDGIVLAGS RMSDAAIRVI AKQKPVVVLG RAVVDVPSVV PDNARGAREV AAHLAGLGHS
ALTYVAGPAA SWADGVRWRA LLEAAEELQL RLRRTGPSSP DVAGGVRAAA ELLAQPTSAV
VAYNDQLAIG VVRGLRGRGV RVPADVSVVG FDNVGAAELV TPGLTTVAAP LQAGGAAATR
ALLAMVQGAP GSTGAPVVLP VRLVVRGSTA QRSRKSTSPA SRTTTVSASA AQASTSTDAG
SR
//
