ID I4F1D1_9ACTN Unreviewed; 1828 AA.
AC I4F1D1;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:CCH89444.1};
GN OrderedLocusNames=MODMU_4042 {ECO:0000313|EMBL:CCH89444.1};
OS Modestobacter marinus.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Modestobacter.
OX NCBI_TaxID=477641 {ECO:0000313|EMBL:CCH89444.1, ECO:0000313|Proteomes:UP000006461};
RN [1] {ECO:0000313|EMBL:CCH89444.1, ECO:0000313|Proteomes:UP000006461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC501 {ECO:0000313|EMBL:CCH89444.1,
RC ECO:0000313|Proteomes:UP000006461};
RX PubMed=22887672; DOI=10.1128/JB.01029-12;
RA Normand P., Gury J., Pujic P., Chouaia B., Crotti E., Brusetti L.,
RA Daffonchio D., Vacherie B., Barbe V., Medigue C., Calteau A.,
RA Ghodhbane-Gtari F., Essoussi I., Nouioui I., Abbassi-Ghozzi I., Gtari M.;
RT "Genome Sequence of Radiation-Resistant Modestobacter marinus Strain BC501,
RT a Representative Actinobacterium That Thrives on Calcareous Stone
RT Surfaces.";
RL J. Bacteriol. 194:4773-4774(2012).
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DR EMBL; FO203431; CCH89444.1; -; Genomic_DNA.
DR RefSeq; WP_014742021.1; NC_017955.1.
DR STRING; 477641.MODMU_4042; -.
DR KEGG; mmar:MODMU_4042; -.
DR eggNOG; COG0210; Bacteria.
DR eggNOG; COG1112; Bacteria.
DR HOGENOM; CLU_000788_0_0_11; -.
DR OMA; KYLMWKD; -.
DR OrthoDB; 3197455at2; -.
DR Proteomes; UP000006461; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:CCH89444.1};
KW Hydrolase {ECO:0000313|EMBL:CCH89444.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006461}.
FT DOMAIN 544..633
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1234..1407
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1453..1549
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1587..1619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1828 AA; 191077 MW; DAD107A8DA711BEE CRC64;
MANVADLQWA PEEPVAPASP AVSADVPEPP AAALAQLAAH VRPEDPAVGA LLAEAAELLE
AGTGSGSMAG WADDAERVDE VVEALTWAVR RREVRWQEIP VDGDPADRPL RSPGELLDGR
TGTALDLVLT LAAAFEQAGL RPLLWLVPGH AFLGYWREER SAGAAATTDV SALVDLVEQG
RIGLVETRLL TDRGNTSADL DGPARSAWLT GDLAGVLGVT DVHRARSEGI RPLPPRTVDA
PPDDDPADDA AEAPAAEPAT QPRTPLQRCA DTLLDLGRGN PLVDLPTGAG LPLAVPPTAL
PVLEDLVGAG ATLTLLATDR AAGPHPEPAP RPAGEPSAEQ LLSEHRSVHG ALPEAEHLPR
LRALAHDART VLEETGANDL HLALGTLVWE LDGAPVRSPL VLVPVVFTVD GRGARLTADE
SGAATPNECL RELLRRQCGL TVPGLDTPSA DGAGTDLTAA LQAVRAAVAE RSLPWRVEPT
AELAVLPLAD VRLWQDLDRH AADLEAHPLV AALTGAPDAA ATDPAPAADV DLDELAARCP
LPADADQLQA VAEGTAGRTF VLEGPPGTGK TQTIANLVTH AVAEGRRVLI VAGKRVALDV
LARRLDAVGL GPITLDLHAR GSRPAVVRAQ VRTALAHAVD VDEPGLTTDA EDLASATRTL
ARYAERLHAE NAGGLSFASA HDALLATDAG TPALPVTPAF AARADADVVT AVRRALALLP
DIAGLARPSA GHAWGFIDSI DLDITAVQQA AAAVDAAVRE LPGEGGLAGA VRAVRSVEDL
DTLLHLLTGP RVTLDVLDEV RSPRWAAATA DVTGEVAALT GAVHPAFETV TPDALALPLA
DLVDRARAVA ATGWWGRRGT LADLREQLAP VLAPGATLRT KDVPALLESL GRLQAAVHGL
AARAVTIPGL QVPAGWNPFV DAGRFVLDAE VRWLRRAAAA VDGSTVPAAA LRRFLTGGPV
ADAASARTVA RLRDAVVTLL AACSSNSAQL AAWSGTDGLV LRWTMTRPER GVEYVHPMSL
RRWVSLLDTL EPLRLAGLTE ARAQLRHGVV RADDAVRAFD RGLAEASVAE RLATTGLDAF
DAGLHESVLS RFTTASRAVR SHLTSAVPAA VLAARPVGAE GEQRVAALQR ELAAHRRGPG
VADLLATDVD LLTTVLPCVL ATPDSVARLL PATAGLFDLV VFDEASRLRV ADAVGALGRA
RAAVVVGDSR QLPPADGQEG LLAACVRAGL PRRSLSWHYR SQDERLIAFS NTRCYDGGLA
TFPAPGHRPS PVSLVQVGGA FLRADGTNPV EARAVVAEVL RRSSAGAASL GVVTLHAGQR
DLVETLLREA GDERVTEALD RLDGEGLLVK QLADVQGDER DVVLLSLGAA PTAGPWTADL
GPLARDGGER WLNVAVTRAR QQVVVVSSFG AAQLPVDEGT APGLAHLRGY LEVAAHGTDA
LPRSAGAPDR HRDQVAAALR ERGLVVRTDV GLSGSRIDLT VARADAPDVP LLAVLLDGPA
WARRRTVGDR DGLPTEVLGE RLGWPAVERV WLPAWLTDRD EVLDRLVAAV DAVPVPVAEE
PAPEPEPEPA YDGPLAEVIP LRPLPTAAVP SAPSAEPLPT ESAPVVEPEA TESALPVESS
GTRSVPLVTA APAVRRAAVP SVLGPLDEEQ PFLPWNPRPA GEKKQLDQLA DPAVAKVVRR
VLAAGLKAEG PVHRDRLTRL AAGAFGLTRV AEARRDALLG LLPRTAVVDG EFVWPAGIDR
ETWTWFRRQA SSAQRPLEHV SPVEIGNAMV ALARAAGGLT EDELVLRTAE VFGHRRRTPA
VAPLLQTALA ATVARGRLTV QPDGRLTA
//
