ID   I4VKE0_9GAMM            Unreviewed;       337 AA.
AC   I4VKE0;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:EIL87681.1};
DE            EC=1.1.1.41 {ECO:0000313|EMBL:EIL87681.1};
GN   ORFNames=UU9_15175 {ECO:0000313|EMBL:EIL87681.1};
OS   Rhodanobacter fulvus Jip2.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Rhodanobacteraceae; Rhodanobacter.
OX   NCBI_TaxID=1163408 {ECO:0000313|EMBL:EIL87681.1, ECO:0000313|Proteomes:UP000004210};
RN   [1] {ECO:0000313|EMBL:EIL87681.1, ECO:0000313|Proteomes:UP000004210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Jip2T {ECO:0000313|Proteomes:UP000004210};
RX   PubMed=22843592; DOI=10.1128/JB.00871-12;
RA   Kostka J.E., Green S.J., Rishishwar L., Prakash O., Katz L.S.,
RA   Marino-Ramirez L., Jordan I.K., Munk C., Ivanova N., Mikhailova N.,
RA   Watson D.B., Brown S.D., Palumbo A.V., Brooks S.C.;
RT   "Genome sequences for six rhodanobacter strains, isolated from soils and
RT   the terrestrial subsurface, with variable denitrification capabilities.";
RL   J. Bacteriol. 194:4461-4462(2012).
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIL87681.1}.
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DR   EMBL; AJXU01000072; EIL87681.1; -; Genomic_DNA.
DR   RefSeq; WP_007082662.1; NZ_AJXU01000072.1.
DR   AlphaFoldDB; I4VKE0; -.
DR   STRING; 1163408.UU9_15175; -.
DR   PATRIC; fig|1163408.3.peg.3082; -.
DR   eggNOG; COG0473; Bacteria.
DR   OrthoDB; 9806254at2; -.
DR   Proteomes; UP000004210; Unassembled WGS sequence.
DR   GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR   PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR   PROSITE; PS00470; IDH_IMDH; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:EIL87681.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004210}.
FT   DOMAIN          4..331
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
SQ   SEQUENCE   337 AA;  36163 MW;  F652F1618E93BFBC CRC64;
     MSNTIAVIPG DGIGPEIMTA TLRVLDALDC GLKYEFVDAG MVALDKHGDL LPKATLDKIA
     EHKVALKGPL TTPIGGGFTS VNVTLRRHFD LYANVRPAVS FPGTKSRYEN IDIITVRENT
     EGAYRSEGQT LSEDGEIAES VARNTRKGSS RIVRYAFELA VKKGRKKITA VHKANILKTS
     SGLFLNVARE IAKEYPQIEF NEMIVDNTCM QLVMRPEQFD VIVTTNLFGD ILSDLCAGLV
     GGLGLAPGDN IGEHAAIFEA VHGSAPDIAG KGIANPCALL LAAADMLDYL DMVAKGDRLR
     QAIRDTMTND RDSVTPDLGG KGSTDSFADA IASRVKI
//