ID I4W045_9GAMM Unreviewed; 401 AA.
AC I4W045;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Efflux pump membrane protein {ECO:0000313|EMBL:EIL92836.1};
GN ORFNames=UU7_10451 {ECO:0000313|EMBL:EIL92836.1};
OS Rhodanobacter spathiphylli B39.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Rhodanobacter.
OX NCBI_TaxID=1163407 {ECO:0000313|EMBL:EIL92836.1, ECO:0000313|Proteomes:UP000003226};
RN [1] {ECO:0000313|EMBL:EIL92836.1, ECO:0000313|Proteomes:UP000003226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B39 {ECO:0000313|EMBL:EIL92836.1,
RC ECO:0000313|Proteomes:UP000003226};
RX PubMed=22843592; DOI=10.1128/JB.00871-12;
RA Kostka J.E., Green S.J., Rishishwar L., Prakash O., Katz L.S.,
RA Marino-Ramirez L., Jordan I.K., Munk C., Ivanova N., Mikhailova N.,
RA Watson D.B., Brown S.D., Palumbo A.V., Brooks S.C.;
RT "Genome sequences for six rhodanobacter strains, isolated from soils and
RT the terrestrial subsurface, with variable denitrification capabilities.";
RL J. Bacteriol. 194:4461-4462(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIL92836.1}.
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DR EMBL; AJXT01000029; EIL92836.1; -; Genomic_DNA.
DR RefSeq; WP_007808060.1; NZ_AJXT01000029.1.
DR AlphaFoldDB; I4W045; -.
DR STRING; 1163407.UU7_10451; -.
DR PATRIC; fig|1163407.3.peg.2099; -.
DR eggNOG; COG1566; Bacteria.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000003226; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003226};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..114
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 216..295
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 296..351
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 165..192
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 401 AA; 42799 MW; 772565E0CDE08D2C CRC64;
MSATESETAV DSNDSGMAAK NPAKRRRALL IVAAVFILAG LIWLLLWMFV FSTRVKTDNA
YVGGNQVAIS AQVPGTVVAI LADDTQRVEA GQVLVKLDAT DAETRLEQAR SALAQAVRGV
RQQTSSATGA DAQVVTARLA LKKAQADLQR RLPLIAAQAE SPEIVQHLRD GVEQARAAVN
AAEAQAAAAH AAIEGTDVAQ NPAVLQARAN FRAAWVAAQR NAIYAPVSGY VAERSVQLGN
SVQPGQQLMT VVPLHDLWID ANFKESQLRH IRIGQPVKIV SDVYGDDAEF HGKVIGLGAG
TGSVFSLLPA QNATGNWIKV VQRVPVRIAL DNRELDKHPL RIGLSTDVTV DIRHDQGSVL
ANTPTQQPVA QTDVYDQMAS KADAEAERII RANLPHATAA N
//
