ID I4YA00_WALMC Unreviewed; 1583 AA.
AC I4YA00;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Myosin 5 {ECO:0000313|EMBL:EIM20792.1};
GN ORFNames=WALSEDRAFT_33020 {ECO:0000313|EMBL:EIM20792.1};
OS Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS
OS 633.66)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=671144 {ECO:0000313|EMBL:EIM20792.1, ECO:0000313|Proteomes:UP000005242};
RN [1] {ECO:0000313|EMBL:EIM20792.1, ECO:0000313|Proteomes:UP000005242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4683 / CBS 633.66 {ECO:0000313|Proteomes:UP000005242};
RX PubMed=22326418; DOI=10.1016/j.fgb.2012.01.007;
RA Padamsee M., Kumar T.K.A., Riley R., Binder M., Boyd A., Calvo A.M.,
RA Furukawa K., Hesse C., Hohmann S., James T.Y., LaButti K., Lapidus A.,
RA Lindquist E., Lucas S., Miller K., Shantappa S., Grigoriev I.V.,
RA Hibbett D.S., McLaughlin D.J., Spatafora J.W., Aime M.C.;
RT "The genome of the xerotolerant mold Wallemia sebi reveals adaptations to
RT osmotic stress and suggests cryptic sexual reproduction.";
RL Fungal Genet. Biol. 49:217-226(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; JH668236; EIM20792.1; -; Genomic_DNA.
DR RefSeq; XP_006959057.1; XM_006958995.1.
DR STRING; 671144.I4YA00; -.
DR GeneID; 18471607; -.
DR KEGG; wse:WALSEDRAFT_33020; -.
DR eggNOG; KOG0160; Eukaryota.
DR HOGENOM; CLU_000192_9_0_1; -.
DR InParanoid; I4YA00; -.
DR OMA; EIMFDDR; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000005242; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF860; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 5.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000005242}.
FT DOMAIN 5..55
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 61..752
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1255..1535
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 632..654
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 911..997
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 154..161
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1583 AA; 178941 MW; CF0EB077AA897C89 CRC64;
MSEYSIGVRV WIADKTEGWI GAEVTAHSGD EITFKDERGT EIIKKSSAND LPLLRNPVLL
EGTDDLVNLS YLNEPAVLYS IKRRYAQHSI YTYSGIVLIA VNPFAKLSIY GPAIMQAYST
RRRGELEPHI YAIAQDAHAS MTRENKNQTM VVSGESGAGK TVSARHIMQY LAFLGQDGTG
SASTGTDASI LATNPVMEAF GNAKTIRNNN SSRFGRYLKI LFDKQCNIIG AQTSIYLLER
SRLIFQPEGE RNYHIFHQLC AGVPPKERAE LHLGSSNDFH YLNQGGSASI PGIDDGAEFE
VTQKALSTLG IGVEKQWNIF KLLASLLHLG NVKIGQTRND AVLNEDDEAF KIATEFLGIN
PSDFKKWTVK KQITTRGESI VSSLNAAQAS VVRDSVAKYI YACLFDWLVA VLNEALYKES
DASKFNSFIG VLDIYGFEHF KRNSFEQFCI NYANEKLQQE FNAHVFKLEQ DEYIKEQIRW
EFISFSDNRP TIDMIEGKLG ILSLLDEESR MPSGTDQNFL EKLHSQLGKP QYKDIYKKPR
FGNTAFTVAH YAHDVAYEAE GFLEKNRDTV PDEHLQLLGS SSNSFLREVI EIAVASNAAA
TPASSTASNN VGVGRRQNLK KPTLGSIFKG SLISLMDTIN DTNAHYIRCI KPNEQKKAWD
IDSQQVLSQL RACGVLETIK ISSAGYPTRW SFAEFTDRYY PLVGSEHWLG DMKELCLQIL
QVNISDEDKY QIGLSKIFFR AGMLAYLEKL RADRLNTLVT LIQKNILRYL HVKHYKKLRE
ATVSIQTWWR KILAIRYVEN LRRDTIIFRL QSAGRRKLAV AKFQNIRRSV IMTQAQIRGM
QARVGFADFK YRSSALNLQR IARGVLARRQ HETSLRGVIH LQACYRRRLA RKEFKQLKSE
ARSVAHIQEV SYKLENKVVE LTQNLQKTRE EKKELTRRCN QLEKQMGNMQ TRHDDADQRM
KEMMVELAKP TVALTDFNEL EALKRDLQTQ VSTLKIDIQE RDKQIQQHKD ELGTQAQEIE
SKSAQAAEAS ARAADETLVN QLKAEIGSLK DQLHRANTLN ALEHGSTKAK QITAPTFSMH
LGKSNENVAA LVNGAGSPVE GDASDALEAL GLPPNKRRQR RHSANGAFLE QNGLGRDTSD
EAFAAGKRSE AAPRAVSLAY PTTDNASKLR GLNGRAYFPE VLDDPSEEMI KLLEDEQSID
DDILTTMIHE LKAPPPSLQN PPSAKEVLFP AHIMSLVTNE MWKYCLIMES ERLLANVMQT
IQQHVMSFQG EDAIVPGLFW LSNVHEVWSF VCVTEDDMLQ GIVPGGDDPD RPLDWPAYEQ
LITVVKHDLE SLEYNIYFAF MEETKKKLRK MIVPALIESQ SLPGFITSDT GGRLFNRLLQ
GNSQPAYNMD DILNLLNKVW KCLKSYRLDE PVVLQVMTEL LRLIGNVGFN DLLMRRNFNS
WKRAMQIQYN LTRLEEWCKS HDLPEGCLHL EYMMQATKLL QLKKATTQDM EIIFDVCWIL
SPSQLHKLIT GYMIADYESP LSPHVLQTVS ARLSSDRNDH LLLAEEEGSN FELPQPRQVI
GLDLYIPGTV SVPHLRRIAG LAA
//
