ID I4YEJ0_WALMC Unreviewed; 985 AA.
AC I4YEJ0;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIM22382.1};
GN ORFNames=WALSEDRAFT_32065 {ECO:0000313|EMBL:EIM22382.1};
OS Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS
OS 633.66)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=671144 {ECO:0000313|EMBL:EIM22382.1, ECO:0000313|Proteomes:UP000005242};
RN [1] {ECO:0000313|EMBL:EIM22382.1, ECO:0000313|Proteomes:UP000005242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4683 / CBS 633.66 {ECO:0000313|Proteomes:UP000005242};
RX PubMed=22326418; DOI=10.1016/j.fgb.2012.01.007;
RA Padamsee M., Kumar T.K.A., Riley R., Binder M., Boyd A., Calvo A.M.,
RA Furukawa K., Hesse C., Hohmann S., James T.Y., LaButti K., Lapidus A.,
RA Lindquist E., Lucas S., Miller K., Shantappa S., Grigoriev I.V.,
RA Hibbett D.S., McLaughlin D.J., Spatafora J.W., Aime M.C.;
RT "The genome of the xerotolerant mold Wallemia sebi reveals adaptations to
RT osmotic stress and suggests cryptic sexual reproduction.";
RL Fungal Genet. Biol. 49:217-226(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH668228; EIM22382.1; -; Genomic_DNA.
DR RefSeq; XP_006957632.1; XM_006957570.1.
DR AlphaFoldDB; I4YEJ0; -.
DR GeneID; 18471419; -.
DR KEGG; wse:WALSEDRAFT_32065; -.
DR eggNOG; KOG0475; Eukaryota.
DR HOGENOM; CLU_003181_2_0_1; -.
DR InParanoid; I4YEJ0; -.
DR OMA; FAECRPG; -.
DR OrthoDB; 150430at2759; -.
DR Proteomes; UP000005242; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd03684; ClC_3_like; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF6; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005242};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 720..745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 985 AA; 108695 MW; 4E1FD0DA9F839F4A CRC64;
MKANDAHTTP RVNLPSDNLN SRLLGTPTNS STTNNRTHFP RTPFASYFGR STESTPLLQS
HINPPSPGQS YFGSRSLGMA INRHRNKSKK HGYDDLYEND MVESGKGVRT YAHTHTSIDY
IHDKVKEGVR LRRLLRKKGI RGFLEKSFDR AQGWFIVTII GIVTAIIAFT IVRTEAWLFS
FRDGYCSNSW LKSKQFCCNI KYTSHQDNFS YLSASMPTLT TDCPEWTSWE DTFGKRSSTL
LNWTMAIAFA FISSIITVYI SASNAPWVND SNSARLEAYH HAASGRKQSV SSPMSCSPQP
HPSLHSHRDS ISSFLYSNGT NKTNSLHSHS LSRKSSSDDD NSLYSDSDNF EEELQANNDE
YADQFDTTNL LSTPTAEKLQ LTSPHNYPVM YFAAGSGIPE MKAILSGFVI RGYLGVCTLL
CKGIGLAFSV ASGLNLGKEG PMVQIAACVG NITSRYIRKF ETNEAKRREI ISASCAAGVS
VAFGAPIGGV LFALEEISTY FPPKVMWRAF YCASLAAVTL KFLDPYGTGK TVLFEVTYDQ
DWKFFELPFF FIIAIAGGLY GAYFSKFNIW WGKNVRMQSI VKSHPIIEVV VITLITAVIS
SYNPLTEMGG TELVSTLLSE CPSKSSGKKL KGIFATLCAR EGQAPWGIIK TLSLAIGIKS
VLTVITFGMK LPAGIFVPTL AVGACFGRMV GLVIEYWSIV QPDSALFGQC KSQSKCMLSA
IYALIGAASA LSGVTRMTIS LVVIVCELTG TLNYVVPTML SILISKTLAD TIEHKGIYDL
IIDMNKLPFL DAKHEYRFGK DSVLDVATKK IPVIRIDQEH SVCTLLDKLD SLVMRGLSDS
GFPLIIDDEG IIRLVGYIAA NELEHALDSL SHNPSARVRF TPFDTLQNSI LTQSTNNSNS
NSRSRLTLFK RFSGVHDAPL SANPYDLSAY CDLSPVVVRP EAPMALVHDN FSKLGARQVF
VVDSIGGFQG VVYRKRWIDY LKSLE
//
