ID I4YEN6_WALMC Unreviewed; 435 AA.
AC I4YEN6;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Clathrin adaptor, mu subunit {ECO:0000313|EMBL:EIM22428.1};
GN ORFNames=WALSEDRAFT_68384 {ECO:0000313|EMBL:EIM22428.1};
OS Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS
OS 633.66)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=671144 {ECO:0000313|EMBL:EIM22428.1, ECO:0000313|Proteomes:UP000005242};
RN [1] {ECO:0000313|EMBL:EIM22428.1, ECO:0000313|Proteomes:UP000005242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4683 / CBS 633.66 {ECO:0000313|Proteomes:UP000005242};
RX PubMed=22326418; DOI=10.1016/j.fgb.2012.01.007;
RA Padamsee M., Kumar T.K.A., Riley R., Binder M., Boyd A., Calvo A.M.,
RA Furukawa K., Hesse C., Hohmann S., James T.Y., LaButti K., Lapidus A.,
RA Lindquist E., Lucas S., Miller K., Shantappa S., Grigoriev I.V.,
RA Hibbett D.S., McLaughlin D.J., Spatafora J.W., Aime M.C.;
RT "The genome of the xerotolerant mold Wallemia sebi reveals adaptations to
RT osmotic stress and suggests cryptic sexual reproduction.";
RL Fungal Genet. Biol. 49:217-226(2012).
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
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DR EMBL; JH668228; EIM22428.1; -; Genomic_DNA.
DR RefSeq; XP_006957672.1; XM_006957610.1.
DR AlphaFoldDB; I4YEN6; -.
DR STRING; 671144.I4YEN6; -.
DR GeneID; 18475385; -.
DR KEGG; wse:WALSEDRAFT_68384; -.
DR eggNOG; KOG0937; Eukaryota.
DR HOGENOM; CLU_026996_0_0_1; -.
DR InParanoid; I4YEN6; -.
DR OMA; KPLIWCD; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000005242; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529:SF262; ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT; 1.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000005242};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 167..421
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 435 AA; 49513 MW; 4B053DCFDBF3AE6F CRC64;
MASLIAILDL KGKSLIQRSY KDDIPPSAVE KFMPIVLEME EDLQTVTPCF SKDGINYMHI
KYSNLYILAL SKSNSNAAEI ILFLHKLASV FTEYFKELEE ESIRDNFVII YELFDEMMDY
GHPQTTESKI LQEYITQESH KLEVQARPPM AVTNAVSWRS EGIRYRKNEV FLDVVESVNM
LVNASGNIIR SEILGAVKMK CFLSGMPELR LGLNDKVMFE TTGRTNRGKS IEMEDVKFHQ
CVRLSRFEND RTISFIPPDG EFELMSYRLS TSVKPLVWAE ASIECHSGSR VEYTVKVKAN
FKKRSSANNV EILIPVPDDA DTPKFRSATG SVSYAPDQSC FIWKIKQLAG GKEFLLRAEF
GLPSVKGDDV QSKRPILVKF EIPYFTVSGI QVRYLKIVEK SGYQALPWVR YLTNDGDYAL
RTNIDRTNNA SSLTN
//
