ID I4YFY3_WALMC Unreviewed; 357 AA.
AC I4YFY3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=RNA-3'-phosphate cyclase {ECO:0000313|EMBL:EIM22875.1};
GN ORFNames=WALSEDRAFT_36105 {ECO:0000313|EMBL:EIM22875.1};
OS Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS
OS 633.66)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=671144 {ECO:0000313|EMBL:EIM22875.1, ECO:0000313|Proteomes:UP000005242};
RN [1] {ECO:0000313|EMBL:EIM22875.1, ECO:0000313|Proteomes:UP000005242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4683 / CBS 633.66 {ECO:0000313|Proteomes:UP000005242};
RX PubMed=22326418; DOI=10.1016/j.fgb.2012.01.007;
RA Padamsee M., Kumar T.K.A., Riley R., Binder M., Boyd A., Calvo A.M.,
RA Furukawa K., Hesse C., Hohmann S., James T.Y., LaButti K., Lapidus A.,
RA Lindquist E., Lucas S., Miller K., Shantappa S., Grigoriev I.V.,
RA Hibbett D.S., McLaughlin D.J., Spatafora J.W., Aime M.C.;
RT "The genome of the xerotolerant mold Wallemia sebi reveals adaptations to
RT osmotic stress and suggests cryptic sexual reproduction.";
RL Fungal Genet. Biol. 49:217-226(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the RNA 3'-terminal cyclase family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00007089}.
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DR EMBL; JH668226; EIM22875.1; -; Genomic_DNA.
DR RefSeq; XP_006956924.1; XM_006956862.1.
DR AlphaFoldDB; I4YFY3; -.
DR STRING; 671144.I4YFY3; -.
DR GeneID; 18471945; -.
DR KEGG; wse:WALSEDRAFT_36105; -.
DR eggNOG; KOG3980; Eukaryota.
DR HOGENOM; CLU_027882_1_0_1; -.
DR InParanoid; I4YFY3; -.
DR OMA; YTDQNKG; -.
DR OrthoDB; 231692at2759; -.
DR Proteomes; UP000005242; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd00875; RNA_Cyclase_Class_I; 1.
DR Gene3D; 3.65.10.20; RNA 3'-terminal phosphate cyclase domain; 1.
DR Gene3D; 3.30.360.20; RNA 3'-terminal phosphate cyclase, insert domain; 1.
DR InterPro; IPR013791; RNA3'-term_phos_cycl_insert.
DR InterPro; IPR023797; RNA3'_phos_cyclase_dom.
DR InterPro; IPR037136; RNA3'_phos_cyclase_dom_sf.
DR InterPro; IPR000228; RNA3'_term_phos_cyc.
DR InterPro; IPR016443; RNA3'_term_phos_cyc_type_2.
DR InterPro; IPR020719; RNA3'_term_phos_cycl-like_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR InterPro; IPR036553; RPTC_insert.
DR NCBIfam; TIGR03400; 18S_RNA_Rcl1p; 1.
DR PANTHER; PTHR11096; RNA 3' TERMINAL PHOSPHATE CYCLASE; 1.
DR PANTHER; PTHR11096:SF1; RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN; 1.
DR Pfam; PF01137; RTC; 1.
DR Pfam; PF05189; RTC_insert; 1.
DR PIRSF; PIRSF005378; RNA3'_term_phos_cycl_euk; 1.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
DR PROSITE; PS01287; RTC; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005242};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 7..333
FT /note="RNA 3'-terminal phosphate cyclase"
FT /evidence="ECO:0000259|Pfam:PF01137"
FT DOMAIN 181..280
FT /note="RNA 3'-terminal phosphate cyclase insert"
FT /evidence="ECO:0000259|Pfam:PF05189"
FT ACT_SITE 315
FT /note="Tele-AMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005378-1"
SQ SEQUENCE 357 AA; 39178 MW; D4755320C97E0E8F CRC64;
MSKSLIRFTG HTFFRQRLVL STLIGRPIRI DAIRAEDDNP GIRDYEAGFL RLLEKITNGS
SVEISYTGTS ILYQPGSLVG GKVTHDCSTS KSIGWYLESI MVLAPFLKKP LNLTLKGITT
DGVDISADTL RTVTLPHLTL FGISEGLELK ITKRGAAPLG GGEVSFSCPT LRQIKTLNFS
DKGRIKRIRG IAHSVRVSPQ LSNRMVEASR SILNRYIPDI YLYTDVYRGE EAGKSPGYAL
TLVAESTTGT LHTAEAVSEP GTTPEDIAKK AAFGLLEEIS HKGAVDRSHQ WLVLLLMSLG
SEDVSKCRMG ELTPHTIQFM RDLRDVLGVT FKIKPLNDDE YMLSCVGIGY TGQKKVA
//
