ID I6Y9K2_MYCTU Unreviewed; 306 AA.
AC I6Y9K2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Probable restriction system protein Mrr {ECO:0000313|EMBL:CCP45322.1};
GN Name=mrr {ECO:0000313|EMBL:CCP45322.1};
GN OrderedLocusNames=Rv2528c {ECO:0000313|EMBL:CCP45322.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP45322.1, ECO:0000313|Proteomes:UP000001584};
RN [1] {ECO:0000313|EMBL:CCP45322.1, ECO:0000313|Proteomes:UP000001584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2] {ECO:0007829|PubMed:21969609}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21969609; DOI=10.1074/mcp.M111.011445;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR EMBL; AL123456; CCP45322.1; -; Genomic_DNA.
DR RefSeq; NP_217044.1; NC_000962.3.
DR RefSeq; WP_003412965.1; NZ_NVQJ01000032.1.
DR AlphaFoldDB; I6Y9K2; -.
DR SMR; I6Y9K2; -.
DR STRING; 83332.Rv2528c; -.
DR REBASE; 6593; MtuHMrrP.
DR REBASE; 73414; MtuHaMrrP.
DR PaxDb; 83332-Rv2528c; -.
DR DNASU; 887150; -.
DR GeneID; 887150; -.
DR KEGG; mtu:Rv2528c; -.
DR PATRIC; fig|83332.111.peg.2826; -.
DR TubercuList; Rv2528c; -.
DR eggNOG; COG1715; Bacteria.
DR InParanoid; I6Y9K2; -.
DR OrthoDB; 9803736at2; -.
DR PhylomeDB; I6Y9K2; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0043590; C:bacterial nucleoid; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015666; F:restriction endodeoxyribonuclease activity; IBA:GO_Central.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:InterPro.
DR Gene3D; 3.40.1350.10; -; 1.
DR InterPro; IPR025745; Mrr-like_N_dom.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR007560; Restrct_endonuc_IV_Mrr.
DR InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR PANTHER; PTHR30015; MRR RESTRICTION SYSTEM PROTEIN; 1.
DR PANTHER; PTHR30015:SF7; TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMRR; 1.
DR Pfam; PF04471; Mrr_cat; 1.
DR Pfam; PF14338; Mrr_N; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE 1: Evidence at protein level;
KW Reference proteome {ECO:0000313|Proteomes:UP000001584}.
FT DOMAIN 7..91
FT /note="Restriction system protein Mrr-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14338"
FT DOMAIN 162..280
FT /note="Restriction endonuclease type IV Mrr"
FT /evidence="ECO:0000259|Pfam:PF04471"
SQ SEQUENCE 306 AA; 33648 MW; 0B314DEDE2260288 CRC64;
MTIPDAQTLM RPILAYLADG QAKSAKDVIA AMSDEFGLSD DERAQMLPSG RQRTMYDRVH
WSLTHMSQAG LLDRPTRGHV QVTDTGRQVL KAHPERVDMA VLREFPSYIA FRERTKAKQP
VDATAKRPSG DDVQVSPEDL IDAALAENRA AVEGEILKKA LTLSPTGFED LVIRLLEAMG
YGRAGAVERT SASGDAGIDG IISQDPLGLD RIYVQAKRYA VDQTIGRPKI HEFAGALLGK
QGDRGVYITT SSFSRGAREE AERINARIEL IDGARLAELL VRYRVGVQAV QTVELLRLDE
DFFDGL
//
