ID I7BJK1_MYCHA Unreviewed; 553 AA.
AC I7BJK1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Magnesium transporter {ECO:0000313|EMBL:AFO52038.1};
GN OrderedLocusNames=MHLP_02290 {ECO:0000313|EMBL:AFO52038.1};
OS Mycoplasma haematolamae (strain Purdue).
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=1212765 {ECO:0000313|EMBL:AFO52038.1, ECO:0000313|Proteomes:UP000006502};
RN [1] {ECO:0000313|EMBL:AFO52038.1, ECO:0000313|Proteomes:UP000006502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Purdue {ECO:0000313|EMBL:AFO52038.1,
RC ECO:0000313|Proteomes:UP000006502};
RX PubMed=23105057; DOI=10.1128/JB.01557-12;
RA Guimaraes A.M., Toth B., Santos A.P., do Nascimento N.C., Kritchevsky J.E.,
RA Messick J.B.;
RT "Genome Sequence of "Candidatus Mycoplasma haemolamae" Strain Purdue, a Red
RT Blood Cell Pathogen of Alpacas (Vicugna pacos) and Llamas (Lama glama).";
RL J. Bacteriol. 194:6312-6313(2012).
RN [2] {ECO:0000313|Proteomes:UP000006502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Purdue {ECO:0000313|Proteomes:UP000006502};
RA Guimaraes A.M.S., Toth B., Santos A.P., Nascimento N.C., Sojka J.E.,
RA Messick J.B.;
RT "Complete genome sequence of 'Candidatus Mycoplasma haemolamae'.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749}.
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DR EMBL; CP003731; AFO52038.1; -; Genomic_DNA.
DR AlphaFoldDB; I7BJK1; -.
DR STRING; 1212765.MHLP_02290; -.
DR KEGG; mhl:MHLP_02290; -.
DR PATRIC; fig|1212765.3.peg.516; -.
DR HOGENOM; CLU_037408_2_2_14; -.
DR OrthoDB; 9790355at2; -.
DR Proteomes; UP000006502; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006668; Mg_transptr_MgtE_intracell_dom.
DR InterPro; IPR006669; MgtE_transporter.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR PANTHER; PTHR43773; MAGNESIUM TRANSPORTER MGTE; 1.
DR PANTHER; PTHR43773:SF1; MAGNESIUM TRANSPORTER MGTE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01769; MgtE; 1.
DR Pfam; PF03448; MgtE_N; 1.
DR SMART; SM00116; CBS; 1.
DR SMART; SM00924; MgtE_N; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR SUPFAM; SSF158791; MgtE N-terminal domain-like; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006502};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 300..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..274
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 553 AA; 60771 MW; 2C939B4807B4AE82 CRC64;
MQLQKQKENL SKNERAVSKL VSRLSRAYEI KNYAVIKEIS IATPAPVLVQ ALEKLSNYEL
INIILLVLKS DRIGSFFLSF SDEHRLGILN TIRPILLSKL LGELSASEVS ELLSIVGSDL
SKKIFYLASP ELRQELNIIS TYSDSQVGSI MTTTMVTIPE NLKINQALNY IKKRRHKFDV
DEELFVINLN KEVVGLVNIQ DLFFSGNNNQ SVSEIVDKDY ISLPAREQIG TAIDLFQKYP
FSSAAIVNDR GQLMGVVTNK DILPEIVDEN LEDVYRFYGI VNLQHSYIKA TTWEVVKSRI
FWLVVLLFAT TLTTFIIDKF ESLGVAWTTG LSSAVLVPMI PLITDMCGNS GSQTAASIIQ
SFASDELKTK DFWNVLKKEL QISVIVGGII SLLNFFRLLV YFSIVPIDAS KIKAAAKTVQ
SVSTLSSAQP TTSYEVVQVS SPSPVILVQA SSGQNNYDNT KLGYVGAGVS SISLFLVIIL
SKLVGVIIPY IAHRCRKDPA SLTTPLLTTL LDAVGTLIFF AIGVGVITLS MNALKTNASM
AANALMPVSF SVA
//
