ID I7BYP3_NATSJ Unreviewed; 471 AA.
AC I7BYP3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Initiation factor 2B-related protein {ECO:0000313|EMBL:AFO58125.1};
GN OrderedLocusNames=NJ7G_2897 {ECO:0000313|EMBL:AFO58125.1};
OS Natrinema sp. (strain J7-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=406552 {ECO:0000313|EMBL:AFO58125.1, ECO:0000313|Proteomes:UP000006507};
RN [1] {ECO:0000313|EMBL:AFO58125.1, ECO:0000313|Proteomes:UP000006507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J7-2 {ECO:0000313|EMBL:AFO58125.1,
RC ECO:0000313|Proteomes:UP000006507};
RX PubMed=22911826; DOI=10.1371/journal.pone.0041621;
RA Feng J., Liu B., Zhang Z., Ren Y., Li Y., Gan F., Huang Y., Chen X.,
RA Shen P., Wang L., Tang B., Tang X.F.;
RT "The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable
RT of growth on synthetic media without amino acid supplements.";
RL PLoS ONE 7:E41621-E41621(2012).
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|RuleBase:RU003814}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003412; AFO58125.1; -; Genomic_DNA.
DR RefSeq; WP_014864790.1; NC_018224.1.
DR AlphaFoldDB; I7BYP3; -.
DR STRING; 406552.NJ7G_2897; -.
DR GeneID; 13349523; -.
DR KEGG; nat:NJ7G_2897; -.
DR PATRIC; fig|406552.5.peg.2545; -.
DR eggNOG; arCOG01127; Archaea.
DR HOGENOM; CLU_568173_0_0_2; -.
DR OrthoDB; 27639at2157; -.
DR Proteomes; UP000006507; Chromosome.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43475; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43475:SF1; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF01008; IF-2B; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:AFO58125.1};
KW Protein biosynthesis {ECO:0000313|EMBL:AFO58125.1}.
FT DOMAIN 36..171
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 471 AA; 50082 MW; 9FDDB3A88DE66756 CRC64;
MVERTAASPE NDSLRAVVAS RMRDSSTAHD GHDEASASHV VTAFLRTRGE VLLLRRSDAV
GTYSGQWGGV SGFAEGRPDE QVRAEIREET GLEAAAVSLV RAGRSVEFTD PALGREWVVH
PYLFDCETRE IELSEEHDAA EWVAPTELLE SVGDDRETVP ELWTAYDRVA PTVRSIAADD
DHGAASLSVR ALEVLRDRAG VIVADRSDSD ADPAAEWDEL AALADRLLEV RPSMAVLRNR
VNRTMADADD RDREAERAGA PAVLESALSN IDRALSADAD AAATASDRLD GTVATLSRSG
TVLEALETAE PSRVFVAESR PACEGVAVAE RLAETTASTV TVHTDAAAAH VLARNAISRV
VVGADTVRPD GSVVNKVGTR ALAIAADHEG IPVSVVAATD KVSTREDVNL EDGARSAVYD
GDAQLDALNP TFDVTPADCI DEIVTERGAL EPDDIAAVAE EVRGLETWRA P
//
