ID I7CWS3_NATSJ Unreviewed; 312 AA.
AC I7CWS3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Biotin/acetyl-CoA-carboxylase ligase {ECO:0000313|EMBL:AFO57221.1};
GN OrderedLocusNames=NJ7G_1979 {ECO:0000313|EMBL:AFO57221.1};
OS Natrinema sp. (strain J7-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=406552 {ECO:0000313|EMBL:AFO57221.1, ECO:0000313|Proteomes:UP000006507};
RN [1] {ECO:0000313|EMBL:AFO57221.1, ECO:0000313|Proteomes:UP000006507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J7-2 {ECO:0000313|EMBL:AFO57221.1,
RC ECO:0000313|Proteomes:UP000006507};
RX PubMed=22911826; DOI=10.1371/journal.pone.0041621;
RA Feng J., Liu B., Zhang Z., Ren Y., Li Y., Gan F., Huang Y., Chen X.,
RA Shen P., Wang L., Tang B., Tang X.F.;
RT "The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable
RT of growth on synthetic media without amino acid supplements.";
RL PLoS ONE 7:E41621-E41621(2012).
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DR EMBL; CP003412; AFO57221.1; -; Genomic_DNA.
DR RefSeq; WP_014864071.1; NC_018224.1.
DR AlphaFoldDB; I7CWS3; -.
DR STRING; 406552.NJ7G_1979; -.
DR GeneID; 13352916; -.
DR KEGG; nat:NJ7G_1979; -.
DR PATRIC; fig|406552.5.peg.1749; -.
DR eggNOG; arCOG01679; Archaea.
DR eggNOG; arCOG01940; Archaea.
DR HOGENOM; CLU_051096_0_0_2; -.
DR OrthoDB; 46252at2157; -.
DR Proteomes; UP000006507; Chromosome.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00978; Bifunct_BirA; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR030855; Bifunct_BirA.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR Pfam; PF08279; HTH_11; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AFO57221.1}.
FT DOMAIN 62..251
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 312 AA; 33244 MW; 10609AF8010F19EF CRC64;
MNETRRAIIA ALADGPVSGP ELAESLDISR AAVWKHIEGL READFEIESG PTGYELVAVD
AYNAPAVEFG LEAPFSIEYH DSVGSTNDRA RELAGEGATD VVVLANEQTG GRGRLDREWA
APAGGVWVSV VTRPAITPAR APLYTLAASV ATATAAREAG VDARIKWPND VVVPVGDDGD
YRKLAGILTE MEGQTDRVDW LVAGIGVNAN LDADALPEGA TSVRAEAGDV DRRRFVQRLL
EEFDRYRGDL EAVVPAWREL ALTIGQHVRV DRPAGEVVGE AIDVTESGAL VVETDDGRVT
VSAGDCEHLR PV
//
