ID I7CYI1_NATSJ Unreviewed; 186 AA.
AC I7CYI1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=isopentenyl-diphosphate Delta-isomerase {ECO:0000256|ARBA:ARBA00012057};
DE EC=5.3.3.2 {ECO:0000256|ARBA:ARBA00012057};
GN OrderedLocusNames=NJ7G_2677 {ECO:0000313|EMBL:AFO57906.1};
OS Natrinema sp. (strain J7-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=406552 {ECO:0000313|EMBL:AFO57906.1, ECO:0000313|Proteomes:UP000006507};
RN [1] {ECO:0000313|EMBL:AFO57906.1, ECO:0000313|Proteomes:UP000006507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J7-2 {ECO:0000313|EMBL:AFO57906.1,
RC ECO:0000313|Proteomes:UP000006507};
RX PubMed=22911826; DOI=10.1371/journal.pone.0041621;
RA Feng J., Liu B., Zhang Z., Ren Y., Li Y., Gan F., Huang Y., Chen X.,
RA Shen P., Wang L., Tang B., Tang X.F.;
RT "The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable
RT of growth on synthetic media without amino acid supplements.";
RL PLoS ONE 7:E41621-E41621(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Isoprenoid biosynthesis; dimethylallyl diphosphate
CC biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate:
CC step 1/1. {ECO:0000256|ARBA:ARBA00004826}.
CC -!- SIMILARITY: Belongs to the IPP isomerase type 1 family.
CC {ECO:0000256|ARBA:ARBA00007579}.
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582}.
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DR EMBL; CP003412; AFO57906.1; -; Genomic_DNA.
DR RefSeq; WP_014864618.1; NC_018224.1.
DR AlphaFoldDB; I7CYI1; -.
DR STRING; 406552.NJ7G_2677; -.
DR GeneID; 13349304; -.
DR KEGG; nat:NJ7G_2677; -.
DR PATRIC; fig|406552.5.peg.2345; -.
DR eggNOG; arCOG01081; Archaea.
DR HOGENOM; CLU_060552_2_1_2; -.
DR OrthoDB; 4234at2157; -.
DR UniPathway; UPA00059; UER00104.
DR Proteomes; UP000006507; Chromosome.
DR GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR011876; IsopentenylPP_isomerase_typ1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR10885; ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE; 1.
DR PANTHER; PTHR10885:SF20; NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PIRSF; PIRSF018427; Isopntndiph_ism; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AFO57906.1};
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229}.
FT DOMAIN 41..179
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 186 AA; 21498 MW; A6BF506768B68035 CRC64;
MSTPEEDLEH ENAGQDVIAV DADDTELELV NRLDAHTGDG IRHRAFTSLV FDGEGNVLLA
QRAPDKRLWG TYWDGTVASH PVEGQSQKEA TRQRLEEELG ITPDQYDDLE LTDRFEYKRY
FENAGVEHEV CAVLQLTLTD RSLDPNEEEV AGLLWVPYER LHSNPAWYRQ LRLCPWFEIA
MRRDVR
//
