ID I7GTA2_9HELI Unreviewed; 599 AA.
AC I7GTA2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Pyruvate carboxylase subunit B {ECO:0000313|EMBL:BAM32123.1};
GN Name=pycB {ECO:0000313|EMBL:BAM32123.1};
GN ORFNames=HCBAA847_0885 {ECO:0000313|EMBL:BAM32123.1};
OS Helicobacter cinaedi CCUG 18818 = ATCC BAA-847.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537971 {ECO:0000313|EMBL:BAM32123.1, ECO:0000313|Proteomes:UP000006036};
RN [1] {ECO:0000313|EMBL:BAM32123.1, ECO:0000313|Proteomes:UP000006036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM32123.1,
RC ECO:0000313|Proteomes:UP000006036};
RX PubMed=23012276; DOI=10.1128/JB.01347-12;
RA Miyoshi-Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RT "Complete Genome Sequence of Helicobacter cinaedi Type Strain ATCC
RT BAA-847.";
RL J. Bacteriol. 194:5692-5692(2012).
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DR EMBL; AP012492; BAM32123.1; -; Genomic_DNA.
DR RefSeq; WP_015453429.1; NC_020555.1.
DR AlphaFoldDB; I7GTA2; -.
DR KEGG; hcb:HCBAA847_0885; -.
DR PATRIC; fig|1206745.3.peg.921; -.
DR eggNOG; COG0511; Bacteria.
DR eggNOG; COG5016; Bacteria.
DR HOGENOM; CLU_000395_4_2_7; -.
DR OrthoDB; 9769961at2; -.
DR Proteomes; UP000006036; Chromosome 1.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Pyruvate {ECO:0000313|EMBL:BAM32123.1}.
FT DOMAIN 2..262
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 524..599
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 599 AA; 66394 MW; B8B0A67B3A9D0B64 CRC64;
MIKITENSLR DGHQSLLATR MRTEDLLQAA EIFDSIGFHS LEVWGGATYD TCLRYLKEDP
FERLYAFKKV CVKTPLQMLL RGQNLIGYRH YADDVVDEFI KLSSQAGMDI FRIFDAFNDG
RNLKTSIESV KKYGKHAQGA ICYTTSPVHT IQSFVEYAKE LVKMGCDSIA IKDMAGLLTP
FVAYDLVKAL KEDICVILSL HTHSTAGFAF GTHLKAVEAG VDVLDLANSA LSEGTSHPCT
QSMVATLQGS KWDSGLDLEP MEKAAEILRK NRRKYKKFES QYNQIDTRVL LSQIPGGMIS
NMANQLKEQN ALDRMDSVMS EIPKVRADFG YVPLVTPSSQ IVGTQAVLNV LMGERYKTIT
TETRNVIKGL YGRTPAALNE SLVKKVLGEG EKIIDVRPAD LLEPELEKAR QDSKEFAKSP
QDVISFAIFG NIAKTFLLER NANALKPEPL ESFEEKCDSK LPKDFNIVVN GEHYEIKVEG
SGERTDEVRP FFIRVDGELK EVFVESIDTS LESKIYKEQK AGALPQATAP GHAKSPMPGT
LTKLKVQVGD KVKLGDTLAI VEAMKMENEV LAPIDGVVKE IYATQGMQIG SDVAIMLLG
//
