ID I7HEP9_9HELI Unreviewed; 443 AA.
AC I7HEP9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Transcriptional activator {ECO:0000313|EMBL:BAM31939.1};
GN Name=flgR {ECO:0000313|EMBL:BAM31939.1};
GN ORFNames=HCBAA847_0701 {ECO:0000313|EMBL:BAM31939.1};
OS Helicobacter cinaedi CCUG 18818 = ATCC BAA-847.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537971 {ECO:0000313|EMBL:BAM31939.1, ECO:0000313|Proteomes:UP000006036};
RN [1] {ECO:0000313|EMBL:BAM31939.1, ECO:0000313|Proteomes:UP000006036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM31939.1,
RC ECO:0000313|Proteomes:UP000006036};
RX PubMed=23012276; DOI=10.1128/JB.01347-12;
RA Miyoshi-Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RT "Complete Genome Sequence of Helicobacter cinaedi Type Strain ATCC
RT BAA-847.";
RL J. Bacteriol. 194:5692-5692(2012).
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DR EMBL; AP012492; BAM31939.1; -; Genomic_DNA.
DR RefSeq; WP_015453348.1; NC_020555.1.
DR AlphaFoldDB; I7HEP9; -.
DR KEGG; hcb:HCBAA847_0701; -.
DR PATRIC; fig|1206745.3.peg.728; -.
DR eggNOG; COG2204; Bacteria.
DR HOGENOM; CLU_000445_0_6_7; -.
DR OrthoDB; 9814761at2; -.
DR Proteomes; UP000006036; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071:SF21; PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..113
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 141..370
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT REGION 116..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 51
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 443 AA; 49512 MW; 0CADB5769D833778 CRC64;
MKIAIIEDDI NYRKSLETAF EDYPQYEIVS FKNPKDALKK LDDSFHLVIT DINMPQMDGL
SFLQELNGRY EAIVITGNAS VQNAIKSIRL GVKDFLVKGF EIEALIEAIE RSHKVHTITQ
NPTKPQDSTN VHKSQKPTKD FISTSLKLEE AKNIALKVAK TDASVLILGQ SGVGKDVFAN
FIHKHSSRAN APFIAINMAA IPEHLLESEL FGYEKGAFTD ATSPKPGILE DANGGSVFLD
EIGEMPLSLQ AKLLRVLQEK SVTRLGSSKP IKIDVRFISA TNANIQAKIA KNEFREDLFF
RLQTIPLSIP PLKERKEEIL PLSEWKLESV CMQYGLGQKR FSKEAKDALL SYEWYGNVRE
LLSVVERAGI LSENDEINPK DLCLESRSQA LGGNSSQKQG ISELEKQLIA QTLTESHNDL
QKASDMLGMN IEVLRHKIAR YGL
//
