ID   I7IA88_9RICK            Unreviewed;       988 AA.
AC   I7IA88;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   13-SEP-2023, entry version 44.
DE   SubName: Full=Type IV secretory pathway VirB6 components {ECO:0000313|EMBL:CCF77969.1};
GN   ORFNames=wOo_01340 {ECO:0000313|EMBL:CCF77969.1};
OS   Wolbachia endosymbiont of Onchocerca ochengi.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia.
OX   NCBI_TaxID=100901 {ECO:0000313|EMBL:CCF77969.1, ECO:0000313|Proteomes:UP000007516};
RN   [1] {ECO:0000313|EMBL:CCF77969.1, ECO:0000313|Proteomes:UP000007516}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Adamawa_Cameroon {ECO:0000313|Proteomes:UP000007516};
RX   PubMed=22919073; DOI=10.1101/gr.138420.112;
RA   Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA   Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA   Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT   "Analysis of gene expression from the Wolbachia genome of a filarial
RT   nematode supports both metabolic and defensive roles within the
RT   symbiosis.";
RL   Genome Res. 22:2467-2477(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family.
CC       {ECO:0000256|ARBA:ARBA00007802}.
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DR   EMBL; HE660029; CCF77969.1; -; Genomic_DNA.
DR   AlphaFoldDB; I7IA88; -.
DR   STRING; 100901.wOo_01340; -.
DR   KEGG; woo:wOo_01340; -.
DR   PATRIC; fig|100901.6.peg.108; -.
DR   eggNOG; COG3704; Bacteria.
DR   HOGENOM; CLU_275316_0_0_5; -.
DR   Proteomes; UP000007516; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007516};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        623..642
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        649..666
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        722..745
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        757..781
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        793..815
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        827..849
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        869..889
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          964..988
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   988 AA;  111030 MW;  1758F5267F582503 CRC64;
     MSKRSLLLAV YFAITGCTID CVEPGLQSRN TSVNVDVPVH KSNKGVKIHW VDSGQTITQG
     EKIKFTLSGS VNFCPLKEGK NQKKVLVPAA FCADDSIPNY SSESINNSGL DEQEVCKNVG
     FGNSQFYSKR RYVDTGIKVN PGDKLSFSLV PKKITINYIN NLEGKDISFD DNCHKTREGD
     KKAMIQDLLN GGTFFCGNDD NRTEIKFPQL SKESFKKRTV LVGNGYTPYD NKVHFNRGYI
     QDESPWINGA LLDLRRAKIG LDKLCNGKDC NFNKVKNYSF TQIGLNQPCT GENCDINKIK
     KYNSYNLNCY YQNICYTKEG IFNSDLYKKG HKNCVSSIRY QKYHKNNQCD IYSHLKSVKD
     KLKEVKNREN SKQVDIIDFT LDTKDISWAE ALVVKINNAG DVSAPESKRD DMKDTAQGTQ
     CLPEKKGAKG DNVCSQISNN FENFSLKLNN DYLVNDNVEP GSNVMLAIAD YGHYYLNRGG
     YHVKTTRSCE YADGKKLYIY LGDNLPENIP TTNNDSFKEV IGLTSIEDNI KYYEIDGSHL
     KNDKPKKIYF GIDVSNVERS DIIDKNGKYY ENNKYSVTLF IKRKINDFIS SSVNKVLNFI
     KREVIGDSIK DLYKGYAKGL SQGVRVLLIL YVIFTVVGYV LGTTQLSKFD FIIRIMKIAF
     ISFAFSDKSW ELFGTTLSKF FVDGSTYLVD SFSGHIGESG KNFAFLDLTT GVLFTRETWL
     KFLSLMLAGP FGFIAFLIIL YASFVSLKCI ISTTFRYVIS TSLVAFLISL TPLFIVFILF
     QQTKSLFENW IKTLAHVAIQ PVILFSFLSI LNQLLYSVLY NLTNFSACYQ CLISINFLSY
     DLCIMKSILP LGYSPSTSID VALGTGERIG GYFAALPIDL IQVFIYLIIA SAMEVFVSAS
     ETIAQAIFGA GWGIMGSIST VTSSASQSIL SIVGLDDKTQ NIIQEIKHKV GKYRPEIEFK
     SKQYELQPAG ENKQSDATNE KGKNVLKK
//