ID   I7ISL5_BABMR            Unreviewed;       620 AA.
AC   I7ISL5;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCF75721.1};
GN   ORFNames=BmR1_04g07665 {ECO:0000313|EMBL:CCF75721.1};
OS   Babesia microti (strain RI).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Babesiidae; Babesia.
OX   NCBI_TaxID=1133968 {ECO:0000313|EMBL:CCF75721.1, ECO:0000313|Proteomes:UP000002899};
RN   [1] {ECO:0000313|EMBL:CCF75721.1, ECO:0000313|Proteomes:UP000002899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RI {ECO:0000313|EMBL:CCF75721.1,
RC   ECO:0000313|Proteomes:UP000002899};
RX   PubMed=22833609; DOI=10.1093/nar/gks700;
RA   Cornillot E., Hadj-Kaddour K., Dassouli A., Noel B., Ranwez V.,
RA   Vacherie B., Augagneur Y., Bres V., Duclos A., Randazzo S., Carcy B.,
RA   Debierre-Grockiego F., Delbecq S., Moubri-Menage K., Shams-Eldin H.,
RA   Usmani-Brown S., Bringaud F., Wincker P., Vivares C.P., Schwarz R.T.,
RA   Schetters T.P., Krause P.J., Gorenflot A., Berry V., Barbe V.,
RA   Ben Mamoun C.;
RT   "Sequencing of the smallest Apicomplexan genome from the human pathogen
RT   Babesia microti.";
RL   Nucleic Acids Res. 40:9102-9114(2012).
RN   [2] {ECO:0000313|EMBL:CCF75721.1, ECO:0000313|Proteomes:UP000002899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RI {ECO:0000313|EMBL:CCF75721.1,
RC   ECO:0000313|Proteomes:UP000002899};
RX   PubMed=24023759; DOI=10.1371/journal.pone.0072657;
RA   Cornillot E., Dassouli A., Garg A., Pachikara N., Randazzo S., Depoix D.,
RA   Carcy B., Delbecq S., Frutos R., Silva J.C., Sutton R., Krause P.J.,
RA   Mamoun C.B.;
RT   "Whole genome mapping and re-organization of the nuclear and mitochondrial
RT   genomes of Babesia microti isolates.";
RL   PLoS ONE 8:e72657-e72657(2013).
RN   [3] {ECO:0000313|EMBL:CCF75721.1, ECO:0000313|Proteomes:UP000002899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RI {ECO:0000313|EMBL:CCF75721.1,
RC   ECO:0000313|Proteomes:UP000002899};
RX   PubMed=27752055; DOI=10.1038/srep35284;
RA   Silva J.C., Cornillot E., McCracken C., Usmani-Brown S., Dwivedi A.,
RA   Ifeonu O.O., Crabtree J., Gotia H.T., Virji A.Z., Reynes C., Colinge J.,
RA   Kumar V., Lawres L., Pazzi J.E., Pablo J.V., Hung C., Brancato J.,
RA   Kumari P., Orvis J., Tretina K., Chibucos M., Ott S., Sadzewicz L.,
RA   Sengamalay N., Shetty A.C., Su Q., Tallon L., Fraser C.M., Frutos R.,
RA   Molina D.M., Krause P.J., Ben Mamoun C.;
RT   "Genome-wide diversity and gene expression profiling of Babesia microti
RT   isolates identify polymorphic genes that mediate host-pathogen
RT   interactions.";
RL   Sci. Rep. 6:35284-35284(2016).
CC   -!- SIMILARITY: Belongs to the RRN3 family.
CC       {ECO:0000256|ARBA:ARBA00010098}.
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DR   EMBL; LN871599; CCF75721.1; -; Genomic_DNA.
DR   RefSeq; XP_012650129.1; XM_012794675.1.
DR   AlphaFoldDB; I7ISL5; -.
DR   GeneID; 24426173; -.
DR   KEGG; bmic:BmR1_04g07665; -.
DR   VEuPathDB; PiroplasmaDB:BmR1_04g07665; -.
DR   Proteomes; UP000002899; Chromosome iv.
DR   GO; GO:0001181; F:RNA polymerase I general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0006361; P:transcription initiation at RNA polymerase I promoter; IEA:InterPro.
DR   Gene3D; 3.10.450.40; -; 1.
DR   InterPro; IPR007991; RNA_pol_I_trans_ini_fac_RRN3.
DR   PANTHER; PTHR12790:SF0; RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED; 1.
DR   PANTHER; PTHR12790; TRANSCRIPTION INITIATION FACTOR IA RRN3; 1.
DR   Pfam; PF05327; RRN3; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002899}.
SQ   SEQUENCE   620 AA;  71185 MW;  AADAD84EA7C8ADDB CRC64;
     MQRGDSSIYC STNSEVINIC TKLLHLKSDN KTEYSRLIEL AILQFKWNVA SSSEISSFSA
     LLIDIITNNT ISLHYVVKFL VKSAKPKIGE FSDIFILNTR FENMQQYSSY ISNLLNKYPN
     KTSITGNEFH IVSELAKNHP SLRYTFNKII GIYSNTTNTS LKSFIVALDD GTSIDLNYAQ
     CLSNITLSSD IWRSKLCDII VDIYRTFPNS HDIILNSLDE NFPHHSFPLE SHVSYLKIFI
     SLSHLLNDSR LKLYRIVISE LIRMDSETQN LQISPTDKGV PLKLDVLMTL LLQDLDFILK
     DPDFDSNAFV SEIFQILKHN IHTLSTSQSV QFIFIYISSL KPYYTEILLQ NLFSILYDEA
     QLLDCRIAAT GYIASLICRQ QLLCDTFIIF TFEYLLKFLG KWSKRAKDNK HIPSNLIKSV
     FEACIRIIYF HADPVLTNIR KYEILRLFSS IIYGSLGTLL NCNIDLLEKA KLSIMRINGP
     NKMLRLLKYL GDRTEKGSNL QLLHLPFDSC NLVYTKYYLM LNSDPDLANT LSGKYISDFH
     IYQDLVVGNI EYDWESRSSD VPKKRFSKYG SSISKDVDGL GDFQLLRAGL TTSIFKPQSK
     SQLDYLLLSD AYKYSKTLYN
//