ID I7IVV0_9LACO Unreviewed; 269 AA.
AC I7IVV0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Mannose-specific phosphotransferase system component IIC high {ECO:0000313|EMBL:CCI82078.1};
GN ORFNames=BN55_01880 {ECO:0000313|EMBL:CCI82078.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI82078.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI82078.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI82078.1}.
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DR EMBL; CAKE01000013; CCI82078.1; -; Genomic_DNA.
DR RefSeq; WP_008471054.1; NZ_CAKE01000013.1.
DR AlphaFoldDB; I7IVV0; -.
DR STRING; 1423758.FC41_GL001166; -.
DR GeneID; 82847301; -.
DR PATRIC; fig|1423758.3.peg.1179; -.
DR eggNOG; COG3715; Bacteria.
DR OrthoDB; 7058816at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR InterPro; IPR004700; PTS_IIC_man.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR PANTHER; PTHR32502:SF25; PHOSPHOTRANSFERASE SYSTEM, MANNOSE-SPECIFIC EIIC; 1.
DR Pfam; PF03609; EII-Sor; 1.
DR PROSITE; PS51106; PTS_EIIC_TYPE_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CCI82078.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 245..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 269 AA; 27855 MW; A69298F06480BB0D CRC64;
MNGIQMILVI LVAFIVGCSS VMDQMETYQP LVACSLIGLV TGHLELGVML GGQLQFIAMG
WANVGAAMAP DASLAGIAAA IILIEGGQGE AGIGTAMGIA VPLAVAGLFL TMLVRTITVG
IAHIMDRKAE EANYKSIERW QFIGLSLQGL RVAIPAALLL AIPANLVRQG LESMPAWLTQ
GMTIGGGMVV AVGYAMVINM MASREVWPFF FLGFALAALQ ELTLISLGII GVVLAILYLS
LEGKGGNGSS NGGSSSDTGD PLGDILDDY
//
