ID I7J661_BABMR Unreviewed; 453 AA.
AC I7J661;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 03-MAY-2023, entry version 31.
DE SubName: Full=Alkaline phosphatase D {ECO:0000313|EMBL:CCF73512.1};
GN ORFNames=BMR1_02g01775 {ECO:0000313|EMBL:CCF73512.1};
OS Babesia microti (strain RI).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=1133968 {ECO:0000313|EMBL:CCF73512.1, ECO:0000313|Proteomes:UP000002899};
RN [1] {ECO:0000313|EMBL:CCF73512.1, ECO:0000313|Proteomes:UP000002899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RI {ECO:0000313|EMBL:CCF73512.1,
RC ECO:0000313|Proteomes:UP000002899};
RX PubMed=22833609; DOI=10.1093/nar/gks700;
RA Cornillot E., Hadj-Kaddour K., Dassouli A., Noel B., Ranwez V.,
RA Vacherie B., Augagneur Y., Bres V., Duclos A., Randazzo S., Carcy B.,
RA Debierre-Grockiego F., Delbecq S., Moubri-Menage K., Shams-Eldin H.,
RA Usmani-Brown S., Bringaud F., Wincker P., Vivares C.P., Schwarz R.T.,
RA Schetters T.P., Krause P.J., Gorenflot A., Berry V., Barbe V.,
RA Ben Mamoun C.;
RT "Sequencing of the smallest Apicomplexan genome from the human pathogen
RT Babesia microti.";
RL Nucleic Acids Res. 40:9102-9114(2012).
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DR EMBL; FO082872; CCF73512.1; -; Genomic_DNA.
DR RefSeq; XP_012648121.1; XM_012792667.1.
DR AlphaFoldDB; I7J661; -.
DR GeneID; 24424138; -.
DR KEGG; bmic:BMR1_02g01775; -.
DR VEuPathDB; PiroplasmaDB:BMR1_02g01775; -.
DR OMA; EHGFETW; -.
DR OrthoDB; 147576at2759; -.
DR Proteomes; UP000002899; Chromosome II.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd07389; MPP_PhoD; 1.
DR Gene3D; 3.60.21.70; PhoD-like phosphatase; 1.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR018946; PhoD-like_MPP.
DR InterPro; IPR038607; PhoD-like_sf.
DR PANTHER; PTHR33987; CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR33987:SF1; CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN; 1.
DR Pfam; PF09423; PhoD; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002899};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..453
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003711104"
FT TRANSMEM 420..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 188..312
FT /note="PhoD-like phosphatase metallophosphatase"
FT /evidence="ECO:0000259|Pfam:PF09423"
SQ SEQUENCE 453 AA; 53454 MW; C9F4270BA5E93386 CRC64;
MSTLHVAPFL ISQLFTIVMC IDYLKESEKL AMYYEKTYGH QLVSLEPDEI ELKALKTLAF
GSCHSLRNAP TEGTTIWDKI SAYKPDLFLW IGDAVYSNET NCDVVKQAYI DMKKYKPYVE
FAKDTRVDGV YDDHDYGIND GDRYFPCKYL TKTYFLDFIN KPKDHYRRNR DGVYFSIEYR
DPKNPNNVVK IILLDVRFNR DPYRHHSHRG KGKISFFLES FRRSIDAYFN LHCSHKGDFL
GETQWQWLEG QLHNSKASAH ILISSIQVYN KCNYQESWKL LPYAQKRLTT LLFKTQPKGL
VILSGDVHYA NIEGDQNLYE ITSSSMTHSF KIKYSKISYI LSILAKHNSN DPYFYNNFGL
IKYEYKDHME ATYLLVNDQG EIVRTYLQRF DESINPYRNL SKSNILCYFF HECFMISKCL
AFLIFILAVP ITYSFYMIFI KFYKKKEAFD TLI
//
