ID I7KCM0_METBM Unreviewed; 310 AA.
AC I7KCM0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Fe-S oxidoreductases {ECO:0000313|EMBL:CCJ36111.2};
GN OrderedLocusNames=BN140_1188 {ECO:0000313|EMBL:CCJ36111.2};
OS Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2)
OS (Methanogenium bourgense).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=1201294 {ECO:0000313|EMBL:CCJ36111.2, ECO:0000313|Proteomes:UP000009007};
RN [1] {ECO:0000313|Proteomes:UP000009007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43281 / DSM 3045 / OCM 15 / MS2
RC {ECO:0000313|Proteomes:UP000009007};
RX PubMed=22965103; DOI=10.1128/JB.01292-12;
RA Maus I., Wibberg D., Stantscheff R., Eikmeyer F.G., Seffner A., Boelter J.,
RA Szczepanowski R., Blom J., Jaenicke S., Konig H., Puhler A., Schluter A.;
RT "Complete genome sequence of the hydrogenotrophic, methanogenic archaeon
RT Methanoculleus bourgensis strain MS2T, isolated from a sewage sludge
RT digester.";
RL J. Bacteriol. 194:5487-5488(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; HE964772; CCJ36111.2; -; Genomic_DNA.
DR RefSeq; WP_024265385.1; NC_018227.2.
DR AlphaFoldDB; I7KCM0; -.
DR STRING; 1201294.BN140_1188; -.
DR GeneID; 13355685; -.
DR KEGG; mbg:BN140_1188; -.
DR PATRIC; fig|1201294.9.peg.1311; -.
DR HOGENOM; CLU_058377_0_0_2; -.
DR Proteomes; UP000009007; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00090; HTH_ARSR; 1.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR040084; GTPase_Obg.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43787; FEMO COFACTOR BIOSYNTHESIS PROTEIN NIFB-RELATED; 1.
DR PANTHER; PTHR43787:SF11; UPF0026 PROTEIN SLR1464; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01083; Uncharacterised_Radical_SAM_Su; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009007};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 13..250
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 310 AA; 34021 MW; F3485A3CD2E7160E CRC64;
MAYRYLFGPV CSRRLGTSLG VDLVPLKTCT FNCVYCECGQ TTSLTRERRE YVPTDRVLAE
VDEYLAKAPN LDYVTFAGSG EPTLHSGIGE IISFIKDRYP RYRVAVLTNS ALLTDPDVRA
ALMQADLIVP SLDAVSEEVF QEINRPCPGL TAGQVLAGLE TFAREFTGEI WLEVFIVPGL
NDMEEEILRL RDAIAAIDPD CVQVNTLDRP GTEVWVRPAP PLALERIASM LGGNAEVIGA
VCMGRALPPK AGEVIDLLLA TIRRRPCTIG DLAGILGLRP AEVSKCLRVL EAEGRVEPVR
EKRGVFYRAI
//
