ID   I7KI33_9LACO            Unreviewed;       317 AA.
AC   I7KI33;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:CCI82650.1};
GN   ORFNames=BN55_07985 {ECO:0000313|EMBL:CCI82650.1};
OS   Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI82650.1, ECO:0000313|Proteomes:UP000009320};
RN   [1] {ECO:0000313|EMBL:CCI82650.1, ECO:0000313|Proteomes:UP000009320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA   Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT   "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT   isolated from human intestine.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCI82650.1}.
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DR   EMBL; CAKE01000034; CCI82650.1; -; Genomic_DNA.
DR   RefSeq; WP_008471797.1; NZ_CAKE01000034.1.
DR   AlphaFoldDB; I7KI33; -.
DR   STRING; 1423758.FC41_GL001647; -.
DR   GeneID; 82847878; -.
DR   PATRIC; fig|1423758.3.peg.1678; -.
DR   eggNOG; COG0583; Bacteria.
DR   OrthoDB; 9803735at2; -.
DR   Proteomes; UP000009320; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd05466; PBP2_LTTR_substrate; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF40; HTH-TYPE TRANSCRIPTIONAL REGULATOR GLTR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          9..66
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   317 AA;  36485 MW;  1AC92BC1967674E8 CRC64;
     MKSNADAVLS AKSLHYFLQL IDSMSYTQAA QILGITQPAL TQQIKKLEKA VGSPLFGQVG
     KRLYLTDAGI EMEETAHKLL NTVQGAIDTI QQYSESDIGQ ISIGALNTFD SSILEEFLVA
     FNRKYPEIKL SFTFYDRKEL WNKMDHNELD FAIIYVPDRN ANPAAMKQYW TEKIYDDSLI
     VLSPKQRRKL EDIVDEKWVS YPKGSYLPQT LTRFYSGKLP EKGLNISARF SETHQMVNFA
     QANKCNTFVT KSFYELNKKN IKLHTVNAIP AVEFQSCFLY RKNKADIPRL SNFLNEWKQF
     LKAKDYSSRL DEYSSLI
//