ID I7L8W8_9LACO Unreviewed; 1113 AA.
AC I7L8W8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Type I site-specific restriction-modification system, R (Restriction) subunit related helicase {ECO:0000313|EMBL:CCI80989.1};
GN ORFNames=BN55_03500 {ECO:0000313|EMBL:CCI80989.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI80989.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI80989.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI80989.1}.
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DR EMBL; CAKE01000001; CCI80989.1; -; Genomic_DNA.
DR RefSeq; WP_008469577.1; NZ_CAKE01000001.1.
DR AlphaFoldDB; I7L8W8; -.
DR STRING; 1423758.FC41_GL000249; -.
DR REBASE; 69586; Lho179TORF3480P.
DR GeneID; 82846272; -.
DR eggNOG; COG4096; Bacteria.
DR OrthoDB; 9758243at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0006304; P:DNA modification; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.90.1570.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR025285; DUF4145.
DR InterPro; IPR013670; EcoEI_R_C_dom.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF13643; DUF4145; 1.
DR Pfam; PF08463; EcoEI_R_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CCI80989.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:CCI80989.1};
KW Hydrolase {ECO:0000313|EMBL:CCI80989.1};
KW Nucleotide-binding {ECO:0000313|EMBL:CCI80989.1}.
FT DOMAIN 353..513
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT COILED 156..183
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1113 AA; 128005 MW; DFF0A79E72AAAAEB CRC64;
MLSVTNFDYL LEEPQFKDFV EIAIAAEKVA VIDPATSVID CRRAMELAVK WMYSVDKDLR
TPYQDKLVTL INTLDFKDIV DPNTWQGLDL IRRLGNVAVH TNRKVSLDEA VLCLKALFSF
FDMLDYCYGS NYQKKDFDKS LIGKYRLEFV PKVAPVKETT VSLDKLTKKN ESLQESMTAQ
RKAQEDSYNP KPFGISEFKT RKIYIDTMLA EAGWVEGQNW LNEVELKGMP NKAGIGYADY
VLYDDAHQPL ALIEAKKTCK DVAVGRQQAK LYADLLEKKY GRRPVVFLSN GFETRIIDNQ
YPERQVSSIY SKRDLEKLFN LQKVRQPLTN ITVDDNIAGR YYQKAAIQAV CESFSKENRR
KALLVMATGS GKTRTAVGLV KVLLNAGWIK HVLFLADRDA LVTQAKRSFV NLLPDLSSTN
LVEDKSNYNA RCVFSTYATM MNVIDTVTDD DKKKLYTAGH FDLIIVDEAH RSIYNKYRNI
FTYFDAPLVG LTATPKDDID KNTYSIFNLE DGVPTYGYDL AQAVDDGYLV PYKSIETHLK
FIENGINYDD LSTQEKEEYE ETFTDEDGDL PKKIDSGKLN KWLFNKDTIR KVLNILMNQS
LKIDYGEKIG KTIIFAKNHR HAEEILKVFN EEYPQFSRNT HGQPYATVID NYTNYSQSAI
DEFSDLDKLP QIAISVDMLD TGIDVPECLN LVFFKKVMSK AKFFQMIGRG TRLCPHLLDG
KDKQEFYIFD FCDNFHFFRM GKGHEAGVQE TLQSALFNLK IELTHKLQEE PYQTDDFKQY
RKTLVEDLSK KVKELNRNNF AVKQHIAYVD KFSQIENYNN LTYEDIVNAQ KELSPLILPD
NGEPNALRFD ALVYKMELAK MSQESYGRLK IDLCNKISKL SDLMTIPQVK EKKDLIKKIL
QPEYVESTDV KDLEHIRQNI RDLIQYLPKK GTVYYTNFAD TVLDSTIHDA ELETDTLKNY
KAKAEFYIKQ HQSENLMVRI RDNEPLSSQD LKELESILWQ KLGSKEEYQK EIGNKAPGEF
VRSIVGLDMH AAKKAFNKYL DTVPLNKQQI YFINEIIEYI VKNGTLTDMH VLQESPFTNQ
GSISELFESD ITIWLKVKTA IDEINSNAGV VVA
//
