ID I7L8X1_9LACO Unreviewed; 313 AA.
AC I7L8X1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Mrr restriction system protein {ECO:0000313|EMBL:CCI80994.1};
GN ORFNames=BN55_03535 {ECO:0000313|EMBL:CCI80994.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI80994.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI80994.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI80994.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAKE01000001; CCI80994.1; -; Genomic_DNA.
DR RefSeq; WP_008469585.1; NZ_CAKE01000001.1.
DR AlphaFoldDB; I7L8X1; -.
DR STRING; 1423758.FC41_GL000244; -.
DR REBASE; 69590; Lho179TMrrP.
DR GeneID; 82846276; -.
DR eggNOG; COG1715; Bacteria.
DR OrthoDB; 9803736at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:InterPro.
DR Gene3D; 3.40.1350.10; -; 1.
DR InterPro; IPR025745; Mrr-like_N_dom.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR007560; Restrct_endonuc_IV_Mrr.
DR InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR PANTHER; PTHR30015; MRR RESTRICTION SYSTEM PROTEIN; 1.
DR PANTHER; PTHR30015:SF7; TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMRR; 1.
DR Pfam; PF04471; Mrr_cat; 1.
DR Pfam; PF14338; Mrr_N; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT DOMAIN 17..103
FT /note="Restriction system protein Mrr-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14338"
FT DOMAIN 170..288
FT /note="Restriction endonuclease type IV Mrr"
FT /evidence="ECO:0000259|Pfam:PF04471"
SQ SEQUENCE 313 AA; 35761 MW; E7DC9975A2E7B3BE CRC64;
MIDYKTLKHS DNGMPTWDAF LGPVLQVAST KDEWIGKELD QAVLDEVNLP EELANLRYAS
KYHDLIAYNR VGWALSEFKL SGLLNSPRRS IYRISETGKE ALDKYGLNIT RDFVHSQPAY
IEHQSNLKNK KEVDNDITED QTFELTEKQI KDWFDKQSSD LSEELIAKLR GTDPYQFEHM
MVRLLNKMGY KGTNGQSVVT QKSNDGGIDG IINQDLLGLR TVYVQVKRYG EKNIVGSPEI
NSFFGALRRK QADRGVFITT SSFTNDARDA AKQLNIALVD GEMLTNLMIQ YKVGVQVSQI
YELYDIDDDF FEE
//
