ID I7L9W0_9LACO Unreviewed; 442 AA.
AC I7L9W0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=BN55_00015 {ECO:0000313|EMBL:CCI81724.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI81724.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI81724.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI81724.1}.
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DR EMBL; CAKE01000008; CCI81724.1; -; Genomic_DNA.
DR RefSeq; WP_008470591.1; NZ_CAKE01000008.1.
DR AlphaFoldDB; I7L9W0; -.
DR STRING; 1423758.FC41_GL001152; -.
DR MEROPS; C01.086; -.
DR GeneID; 82846964; -.
DR PATRIC; fig|1423758.3.peg.1165; -.
DR eggNOG; COG3579; Bacteria.
DR OrthoDB; 1111399at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00585; Peptidase_C1B; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR10363; BLEOMYCIN HYDROLASE; 1.
DR PANTHER; PTHR10363:SF2; BLEOMYCIN HYDROLASE; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000256|PIRNR:PIRNR005700};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR005700};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807,
KW ECO:0000256|PIRNR:PIRNR005700}.
FT ACT_SITE 70
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 364
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 385
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 442 AA; 51681 MW; 0565B6E2E0490C02 CRC64;
MLQDLDPEDL KKMRSDFLEN DKYRNTQNAV MENGIKKSIT NKSVIESHPF VFSIDVDSDD
VMNQKHSGRC WMFSAMNFIR HHVEKEHHMK NFELSTDYMF FYDKLERANY FYHNVIDTAD
QPLSDRKVNW LMHTPQQDGG DWSLLVSLME KYGVVPASVM GETAVSANTT ELNFAFNRKL
QKDAMKLRNL VNSDASDEKL ASELRRMNSE NYKILAISFG TPPEKFNFSY RDENNQYHTI
GEVTPLEFFK KFVDINLNDY VELMNIPGLG YKYNQVYTIQ LSKNMVDGIE NRYLNVSMDE
MNKLMLEQLK DGTPVWFGCD VLQEYNRPTG SLELGLYDWK RSFGFSLGKD KAERFEYGES
LPTHAMLICG VELHDNKPIN WKIQNSWGNK VGHLGYFMMG EKWMNAYTYE IVINKKYLSD
QQLSAYDKEP IELPYYNAFN PI
//
