ID I7LXG3_TETTS Unreviewed; 210 AA.
AC I7LXG3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Charged multivesicular body protein 1a {ECO:0000256|ARBA:ARBA00020509};
DE AltName: Full=Chromatin-modifying protein 1a {ECO:0000256|ARBA:ARBA00032184};
GN ORFNames=TTHERM_00239080 {ECO:0000313|EMBL:EAS04588.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS04588.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; GG662443; EAS04588.2; -; Genomic_DNA.
DR RefSeq; XP_001024833.2; XM_001024833.3.
DR AlphaFoldDB; I7LXG3; -.
DR STRING; 312017.I7LXG3; -.
DR EnsemblProtists; EAS04588; EAS04588; TTHERM_00239080.
DR GeneID; 7829935; -.
DR KEGG; tet:TTHERM_00239080; -.
DR eggNOG; KOG3232; Eukaryota.
DR HOGENOM; CLU_085558_0_0_1; -.
DR InParanoid; I7LXG3; -.
DR OMA; MDPMKIA; -.
DR OrthoDB; 187505at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007034; P:vacuolar transport; IEA:InterPro.
DR Gene3D; 6.10.140.1230; -; 1.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR10476; CHARGED MULTIVESICULAR BODY PROTEIN; 1.
DR PANTHER; PTHR10476:SF17; CHARGED MULTIVESICULAR BODY PROTEIN 1A; 1.
DR Pfam; PF03357; Snf7; 1.
PE 4: Predicted;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 25..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 210 AA; 23883 MW; AE9C4EC950CFFAC3 CRC64;
MGNEAPKPAP AKPVDPMDAI LDMKMTSKQF ERESKKAEQE SKKLVEKAKQ ALQKGNEEGA
KLYLQNSSMK QKHSISMMRM ANKLDAVQCQ MKMAQGNTQM VAQLNKITPY LQFHSQNLPL
EQMYGQMANF EQAMDEITVQ QKVMDGVMNK NDIGTDVAVD NMLNQLKMEN AMEINQKLQQ
SNNAVFNDIK NNNQNLINQN PNNVQEFKQI
//
