ID   I7LZT5_TETTS            Unreviewed;       905 AA.
AC   I7LZT5;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Leucine rich repeat protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TTHERM_00600790 {ECO:0000313|EMBL:EAR84887.1};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR84887.1, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA   Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA   Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA   Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA   Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA   Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA   Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT   model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
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DR   EMBL; GG662620; EAR84887.1; -; Genomic_DNA.
DR   RefSeq; XP_001032550.1; XM_001032550.1.
DR   AlphaFoldDB; I7LZT5; -.
DR   STRING; 312017.I7LZT5; -.
DR   EnsemblProtists; EAR84887; EAR84887; TTHERM_00600790.
DR   GeneID; 7839393; -.
DR   KEGG; tet:TTHERM_00600790; -.
DR   eggNOG; KOG0531; Eukaryota.
DR   eggNOG; KOG1836; Eukaryota.
DR   HOGENOM; CLU_341458_0_0_1; -.
DR   InParanoid; I7LZT5; -.
DR   OMA; DHASYEH; -.
DR   OrthoDB; 180444at2759; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF12799; LRR_4; 1.
DR   SMART; SM00365; LRR_SD22; 4.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT   COILED          302..378
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          407..480
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          596..901
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   905 AA;  107938 MW;  44576652CCCABA0E CRC64;
     MADYNKSNDD LTESIDELEY GGYNIKENTI SNIIDLQDKI KIKYIRIMHS EALQSMIGLS
     RFTRLEEINL SSNSIIKIDG LDGLSNLKIL NLSCNKLSEL SGLGSLFRLE KLIVSHNKIT
     NLSGLQQMAG PNYNIKSIDL KNNKIRDVKQ LQYIQDLSKL QELCFEMGKN SNPLCTENRS
     IYLQGLTSMR NFQRILRIDG QTPENIIENI KYQGQIQNQN FNNLNNLATL PNSGNQGRNI
     QIADQTNPKS GNLNAFPSQG QRPISNLMSF NDQSANKKIS IGDQGDLIGD NFKWKGDHLQ
     MQQDLQQALQ IQKELINKYE VNDKFWEQKY EKLQEEFNQV QEDNRQKTQK IKTMSKEKQF
     LEEQISEIKN ERIRMLNKTE KREEIVETLQ LRITDLIKEN GQYHRELAIR QDQMDKQASE
     IKNLQEDLIE MRGRLRENEQ TLSEFHKKAL DQTNSYVTKY EQINKKYEQV LEENKLMANE
     NGMLKTRVQE LLEITREWEY KYEKKVDELN YKHEQYIRDI QQEFSQREQS QEKQLREWEK
     VKEDEFKENI ELMEQEFKKY FLENNNRFRE LSRAYEEKCK QEQDSRHLMK VAVQKNSDQA
     NLIEELQNAL LKVKKEVSEI VNERDVAQKE LDTKKSTYMR EVSSLEEERD RLLHDKLSLE
     RQLQDIQDRN MTDNLELERL RAKMKYFENI EEDLEKCQET VQAKNIMLED KNDTIEDLKD
     QLEQSRQREQ VLNDDFNKIQ KKYEKQNQII EALEEQLQQA NEEADSINEE KINLQKELEK
     KKEIIDIFQN EFNDIKSKQD KEINEKSNKI QDLLYLLEEC KQNIRRKDEQ IADLQNEIKD
     RNEKYEVQLI MLQNEQKQKD KALKELQNKY DESQEDMKQL IIEYEKQKKQ TLEQFQKLQK
     NLFNF
//