ID I7M7W9_TETTS Unreviewed; 241 AA.
AC I7M7W9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Ser/thr phosphatase family protein {ECO:0000313|EMBL:EAR96157.1};
GN ORFNames=TTHERM_00129330 {ECO:0000313|EMBL:EAR96157.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR96157.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662699; EAR96157.1; -; Genomic_DNA.
DR RefSeq; XP_001016402.1; XM_001016402.3.
DR AlphaFoldDB; I7M7W9; -.
DR EnsemblProtists; EAR96157; EAR96157; TTHERM_00129330.
DR GeneID; 7825666; -.
DR KEGG; tet:TTHERM_00129330; -.
DR eggNOG; KOG3947; Eukaryota.
DR HOGENOM; CLU_041441_1_0_1; -.
DR InParanoid; I7M7W9; -.
DR OMA; NIPTLGM; -.
DR OrthoDB; 5471007at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd07379; MPP_239FB; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR12905:SF0; METALLOPHOS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12905; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 12..203
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 241 AA; 27370 MW; 77D02B0A889911F5 CRC64;
MDSSNQDGSF IKFVCISDTH TKAGLLNLPK GDVLIHAGDF TYTGKPEEVY EFNDFLKNSD
FEAKVVIAGN HDLTFDIQNY AKDYAQRFHQ DEKIPIDAVA TKAMLKDCIY LEDSSVNLKG
YSIYGSPYTP TFFDWAFNLD IGKPLQKKWE QIPNNTDILI THGPPHKILD RCYDGFQAGC
PDLRKAVLER VKPLYHIFGH IHEDFGQLKI DNTTFINASS VDFKYKTRSS PAITFSLPIK
D
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