ID I7M9D2_TETTS Unreviewed; 572 AA.
AC I7M9D2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
GN ORFNames=TTHERM_00149750 {ECO:0000313|EMBL:EAS01364.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS01364.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC -!- SIMILARITY: Belongs to the TBCC family.
CC {ECO:0000256|ARBA:ARBA00008848}.
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DR EMBL; GG662603; EAS01364.1; -; Genomic_DNA.
DR RefSeq; XP_001021610.1; XM_001021610.3.
DR AlphaFoldDB; I7M9D2; -.
DR STRING; 312017.I7M9D2; -.
DR EnsemblProtists; EAS01364; EAS01364; TTHERM_00149750.
DR GeneID; 7826031; -.
DR KEGG; tet:TTHERM_00149750; -.
DR eggNOG; KOG4416; Eukaryota.
DR HOGENOM; CLU_476954_0_0_1; -.
DR InParanoid; I7M9D2; -.
DR OMA; NCEDSYI; -.
DR OrthoDB; 177735at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR039589; TBCC1.
DR InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR Pfam; PF07986; TBCC; 1.
DR SMART; SM00673; CARP; 1.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 257..421
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
SQ SEQUENCE 572 AA; 65316 MW; BC56B86F81A8C36E CRC64;
MNSSSSSGSI NDSQQVLHIR SDVFEHAVFP TPAKLTLINL VHLFGSLNQV ANKEKKITLE
QFKEHIQKHT SNINEKDAEI YFLTYKMVTE DDVSFVIQAA KKQSTSSTVQ QQQNQMPILY
ADVRGLAVFF FLQLFSISAR NQFSMDFRKS EFNTHFNEGF RGNLSHNFSP LNSPRSKTTR
TTPQFSSEQQ QAIYYIRYNI KTILKLLSND IDNEDCSLKA QDFNVLQLIL KPDISQLNKI
TLPSQFQASK LAQLNLPPTL SQYSGKFNKE DKVHMNTLSE YISSSISMNE QAIDVIYIQG
LTKSVMCKDE KFCAGQDLRI LNCEDSYIYI DAAVQSLSVT NCTNTTIFIS AVNKICTIDK
SENLTITVAS NFLRIGNTID STVYYYGSYY PVLYGDNRSV TLAPNNANYL DLFERMKQAK
IPLNYKSSLN FASPIVMNQN QAMSYTVLPT KEFFPINLPP QFKPVSHSQV QTFEQILSPQ
FEKYLIDQKN NQQESVSTNM IIPLLAPNDY RDQVIQRFKL YTDYQTMLKN SGLSDSQSKM
LQSAIQGYFR EWMVQTGQIK PISDLVKMIN QD
//
