ID I7MA54_TETTS Unreviewed; 675 AA.
AC I7MA54;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Alpha/beta hydrolase fold protein {ECO:0000313|EMBL:EAS03744.1};
GN ORFNames=TTHERM_00475070 {ECO:0000313|EMBL:EAS03744.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS03744.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG662472; EAS03744.1; -; Genomic_DNA.
DR RefSeq; XP_001023989.1; XM_001023989.1.
DR AlphaFoldDB; I7MA54; -.
DR STRING; 312017.I7MA54; -.
DR ESTHER; tetts-q246g7; Hormone-sensitive_lipase_like.
DR EnsemblProtists; EAS03744; EAS03744; TTHERM_00475070.
DR GeneID; 7829503; -.
DR KEGG; tet:TTHERM_00475070; -.
DR eggNOG; KOG4388; Eukaryota.
DR HOGENOM; CLU_387101_0_0_1; -.
DR InParanoid; I7MA54; -.
DR OMA; YVEMSHY; -.
DR OrthoDB; 5476228at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR Pfam; PF07859; Abhydrolase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EAS03744.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 406..622
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
SQ SEQUENCE 675 AA; 79165 MW; EC0D39B57000315F CRC64;
MSDLNLDLFT RFKNIFINLD FEFKRLLQSE KYNGSVTLNK EVWTMKEILE WFIQITTDNL
KLINQINHQI QGKYDDETVF IHQEIKNLKR EELNLYYLIK GCKHFNEDLI QTLANVRLID
SESEFKKRIP MIYVEMSHYR LMFDHNIYHS ILSASQNDIM MHFDDKDHPE YKFVKQRLEY
INILEKAEYV KEALEKFGHL SNLSNCALVR TVSKDSSKLK ALLETFWIVF YYLQPKKSLE
ETKVFQVNPS NELVIAIWNV FERLYPMRLF LKTSLPKVTQ RLKIYVPPVY EPITLKEIIE
KNTSKTMFDL KADQHKIPQP VHFKRAVDSV QIQAMENINA SNLQERNQNV QTEWKKYNLF
DKSNKQSIKV TILSNIPLIA REIVGKSNEE YQPKKNGPKL IQDIVYHIHG GGWVGLNTLS
HEMYTRKWAK DLGDIPIFSV EYSNAPENKY PKPLDDCWQV YQFLLNGLEE YFENVKIRKI
IIAGDSAGGN MALGICLLAL QRGIRRPDGL ILSYPALNLR MDFFTPSFIN IFKEIIIPFN
FLKVSLDSYM DRTNPNIDPN SDPLLSPILF SDEVLQQLPP IRMACGDKDL LKDDCIRFLQ
KLIKLNHNVK LLLYRELTHG YLNLDLPMTL PATKKCGYDC VLFAKQLLSG ETLKPIEHFN
ERILEQQQLL EQKNN
//
