ID I7MF20_TETTS Unreviewed; 356 AA.
AC I7MF20;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Acyltransferase {ECO:0000313|EMBL:EAR98330.1};
GN ORFNames=TTHERM_00285610 {ECO:0000313|EMBL:EAR98330.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR98330.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
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DR EMBL; GG662651; EAR98330.1; -; Genomic_DNA.
DR RefSeq; XP_001018575.1; XM_001018575.3.
DR AlphaFoldDB; I7MF20; -.
DR STRING; 312017.I7MF20; -.
DR EnsemblProtists; EAR98330; EAR98330; TTHERM_00285610.
DR GeneID; 7839488; -.
DR KEGG; tet:TTHERM_00285610; -.
DR eggNOG; ENOG502QWZ2; Eukaryota.
DR HOGENOM; CLU_812549_0_0_1; -.
DR InParanoid; I7MF20; -.
DR OMA; LWKNEIF; -.
DR OrthoDB; 178629at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR23063:SF1; LYSOPHOSPHATIDIC ACID:OLEOYL-COA ACYLTRANSFERASE 1; 1.
DR PANTHER; PTHR23063; PHOSPHOLIPID ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EAR98330.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..237
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF01553"
SQ SEQUENCE 356 AA; 41345 MW; DEC37B319250C70F CRC64;
MEKYRRFADQ FTGINPFLPV FLNKKKKASE IILKLLLGPI LVLIRLPLIL IFALLLVLYH
SIFIHLLVVN SFKRVVTLFN HLVCLRVILF LMGFYKFKTS FKILSKEGSN KSPPPKMNSG
FIVLANHTSP VDYIYMTYLM SPIFSKQYIS TKDSSQTKVL LSPLSFFQTI KAAFSLDYSI
PVQGDDTELA KHHDQKLKVI SLIQSSFDEH KGPLCVFFEG AKTNGYGFLQ AEESLIQDIA
EVQEKYRREV VVFNLKYTDK SHFSPINTTR NPFLHFILLL TNFSNELKVS AKGIPFQDTT
QTGPLDIKQY KESIYSFYES SGIKKMQVTW REYQKFLDYW QNSQSKQYIE EIKKRE
//
