ID I7MJS6_TETTS Unreviewed; 668 AA.
AC I7MJS6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=FHA domain protein {ECO:0000313|EMBL:EAS07155.2};
GN ORFNames=TTHERM_00646880 {ECO:0000313|EMBL:EAS07155.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS07155.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662245; EAS07155.2; -; Genomic_DNA.
DR RefSeq; XP_001027397.2; XM_001027397.2.
DR AlphaFoldDB; I7MJS6; -.
DR STRING; 312017.I7MJS6; -.
DR GeneID; 7833600; -.
DR KEGG; tet:TTHERM_00646880; -.
DR eggNOG; KOG2294; Eukaryota.
DR InParanoid; I7MJS6; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0060962; P:regulation of ribosomal protein gene transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd22701; FHA_FKH1-like; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR045178; Fhl1/FHA1.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR21712:SF29; PRE-RRNA-PROCESSING PROTEIN FHL1; 1.
DR PANTHER; PTHR21712; UNCHARACTERIZED; 1.
DR Pfam; PF00498; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 383..434
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 309..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..523
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..668
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 78364 MW; E772B4D7648A111E CRC64;
MSEIKSMSTR EKIGTTTRRL IKYLYENRNQ VFKLDKIFDD VQSFISDQKK LIDLVFILDG
IGILTRISKK KFVFTGLKGM CNRINEYIKR KIQKASNQRE VQMFCDEIQV NGKKISIKSS
ITQGQLFQDV LCNLTLQPNK LLQRSQFEQI MESYREIQSK SLTNDLNNIL MTLCLGERNE
TTETIQYTGP EILNYKKITL DTLKNVNPNS LKTVILDSQK KDNIYFSYLI KEVDEKRGKK
NTLQSGLFKE LALEQGEIDK INRIVAQSML STNGSYFSQA ATSQQAVNQA AQNQQKQEVQ
IEITNTKQET EQVQNNNDND QTAENQSELN DKDIEENDKN MNQNEDTIDI TDVPKAHISY
FPKVAFALLK GRTWQFYIQK LQIIIGRSLI NLPQKKMNWH IDLEVGASKK VSRQHAVILY
NFEQKRFEIK CLSKKFHIKV DNNLYSIKDD PVPLKNKSLI TVGNEHFYFF LPKNLTDEIQ
KKHEKILPDE MNAERGRREE DEDQTRNREE GDEEDDDEME GDGEEDDRRY RQRRNMSMDG
EEEDDEGESL SEIENKSTNR KKLKRNQDDY DNNEDYDYYQ NREPNSEEDG NNDFLNEEEK
EFLKKTNQNV NNNEEEEDDE QEIEDDDDDD DGDNDDDDEG DEEVDDEDEE VENEDEEEEE
EMEQSEDE
//
