ID I8TDW4_9GAMM Unreviewed; 595 AA.
AC I8TDW4;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Cyclic nucleotide-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WQQ_23070 {ECO:0000313|EMBL:EIT72170.1};
OS Hydrocarboniphaga effusa AP103.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Nevskiales; Nevskiaceae;
OC Hydrocarboniphaga.
OX NCBI_TaxID=1172194 {ECO:0000313|EMBL:EIT72170.1, ECO:0000313|Proteomes:UP000003704};
RN [1] {ECO:0000313|EMBL:EIT72170.1, ECO:0000313|Proteomes:UP000003704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP103 {ECO:0000313|EMBL:EIT72170.1,
RC ECO:0000313|Proteomes:UP000003704};
RX PubMed=22933753; DOI=10.1128/JB.01017-12;
RA Chang H.K., Zylstra G.J., Chae J.C.;
RT "Genome Sequence of n-Alkane-Degrading Hydrocarboniphaga effusa Strain
RT AP103T (ATCC BAA-332T).";
RL J. Bacteriol. 194:5120-5120(2012).
CC -!- SIMILARITY: Belongs to the NTE family. {ECO:0000256|ARBA:ARBA00006636}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIT72170.1}.
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DR EMBL; AKGD01000001; EIT72170.1; -; Genomic_DNA.
DR RefSeq; WP_007185250.1; NZ_AKGD01000001.1.
DR AlphaFoldDB; I8TDW4; -.
DR STRING; 1172194.WQQ_23070; -.
DR Proteomes; UP000003704; Unassembled WGS sequence.
DR GO; GO:0004622; F:lysophospholipase activity; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd07205; Pat_PNPLA6_PNPLA7_NTE1_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR14226:SF29; NEUROPATHY TARGET ESTERASE SWS; 1.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF01734; Patatin; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000003704};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 12..128
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 320..480
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 595 AA; 65051 MW; D92E5C5AD9CDD37E CRC64;
MDIPTLLAQT PLLAGIDGPA LATLAERSVV CSFRSGQTVF NIGALADCLY IVGIGRLRVD
NADGSLRGEV GLHECVGEIA TLGNRMHSGH VYAVRDSYLL RIDRSVLLDF VQRHPAALLR
LTQVIIDRLQ MRHTPASLAH ARRPRALALV PATPDIDIAD LARQLRGTLS ECGHTGIVDA
HRVDTAIAPG MAQTLQDDAD ADRLTRLLHA GETQFRHLLY LTDAHPSAWS ARCLRQSDRV
LVVVSAKTPP HATPMLDLLR DLRLRVPIEL IVLRSDGAEA EHVLAWRELA GARAHYFLRP
GYDGDAARIA RSLTGRALGV VMGGGGARGF AHIGLLRALQ ELSLPLDVLG GSSMGAFVGG
LAACGLNWKQ ILEVARETFV RRKLLNDYLL PRVSLIRGRK FYRQLENVFG EQQIEQLRTP
YFCVSTNLTR GQSVVHERGS MAMWIATSMA VPGVAPPVVW RGDLLVDGAV ANSLPTDVMQ
ELERGPILAS DVSTEGTLTM PGIEGPDIDA VLRWTPTDDE ARRPTLMSIL FRTATLTSES
GVRQRAQRAD AYLRLPVSGV ALFDWKRLDE LADRSYEFAM QKLPALRAQL LACPI
//
