ID I8XTN6_9BACE Unreviewed; 1204 AA.
AC I8XTN6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=F5/8 type C domain-containing protein {ECO:0000259|PROSITE:PS50022};
GN ORFNames=HMPREF1068_00607 {ECO:0000313|EMBL:EIY53437.1};
OS Bacteroides nordii CL02T12C05.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY53437.1, ECO:0000313|Proteomes:UP000003089};
RN [1] {ECO:0000313|EMBL:EIY53437.1, ECO:0000313|Proteomes:UP000003089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY53437.1,
RC ECO:0000313|Proteomes:UP000003089};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY53437.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGXS01000011; EIY53437.1; -; Genomic_DNA.
DR RefSeq; WP_007483493.1; NZ_JH724314.1.
DR AlphaFoldDB; I8XTN6; -.
DR STRING; 997884.HMPREF1068_00607; -.
DR PATRIC; fig|997884.3.peg.616; -.
DR eggNOG; COG0383; Bacteria.
DR HOGENOM; CLU_277670_0_0_10; -.
DR Proteomes; UP000003089; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR Gene3D; 2.60.40.2220; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
DR PROSITE; PS50022; FA58C_3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003089};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1204
FT /note="F5/8 type C domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003716806"
FT DOMAIN 1058..1204
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 1204 AA; 135780 MW; 52C87F8C506CFD36 CRC64;
MKKHIIALAS TLLLCSGSYS QNTQPEKKPK AYMVADAHLD TQWNWDVQTT IKQYVWNTIS
QNLLLLKQYP DYIFNFEGGV KYAWMKEYYS AQYEEMKKYI REGRWHVSGA SWEASDALVP
STESAIRNIM LGQEYYRKEF GVESTDIFLP DCFGFGWTLP TIAAHCGLIG FSSQKLDWRN
KPFYGKSKHP FTIGLWQGID GSSVMLAHGY DYGKRWNDED LSENKELLGL TTRTPLNMVY
RYYGTGDIGG SPTLGSVRSV EKGIKGNGPL EIISATSDQM FKDFQPYKDH PELPVFNGEL
LMDVHGTGCY TSQAAMKLYN RQNELLGDAA ERAAVAAEWL NKAAYPGTTL TDAWKRFIYH
QFHDDLTGTS IPHAYEFSWN DELISLKQFS GVLASSIRSI AGDMDTQVKG IPVILYNALG
FPVQDIAEVE LEVPAAPKGV TVYDNNGKKV ASQLLSYTNG KAHLLIEATV PATGYAVYDV
RTSGTANRFA ATTSNTLENS IYKITLDEKG DITSLLDKTQ NKELVKQGKA IRLALFTQNK
SYHWPAWEVL KETIDREPIS ITDNVKISLV ENGELRKAIC IEKTHGESVF KQYIRLYEGS
RADRIDFYNE IDWQSTNALL KAEFPLNIEN TEVTYDLGIG SVKRGNNTDI AYEVYAQYWA
DLTNQDNSYG VSILNDSKYG WDKPNNHTLR LTLLHTPETT RNYAYQDKQD YGHHNFTYSL
VGHSGKLDHA STVEKAELMN QRLKAFQTTK HKGTLGKEFS FATSDNRNVI IKALKKAESS
DEYVVRVYET GGEKSQQATL SFAGDILNAN EADGTEKTIG AANFNGNKLQ ITIKPYSVKT
FKVRLKSAAQ PASEPEYVNL PLNYDRKCAS FNEFRGEANF ESGYSYAAEL LPDSIFADQI
PFRLGEKETF NGMTCKGDTI YLPDGHKYTH LYFLAAATDD DYTVTFCCGK NKAEITVPSY
TGFIGQWGHT NHTKGYLKDA EIAYVGTHRH APGEDQPYEF TYMFKFGIDI PKGAVSFILP
KNDKIVLFAA TLAKEEQPAV NTASQLFRTA IREEAGKILS TQESPKENLL KTAKIISYSG
YMNNREKPEC MIDGNKDTKW CDTGMTPNYV DFDLGEAQDI SGWKLVNAGE ESHTYVTKGC
FLQGKNNLNE EWKTLDRLNN NKRNVVSRQL SEPAKVRYIR LMVTNPTQDD EGKDTRIYEF
EVYK
//
