ID I9GYF5_9BACE Unreviewed; 840 AA.
AC I9GYF5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Beta-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1068_01726 {ECO:0000313|EMBL:EIY52179.1};
OS Bacteroides nordii CL02T12C05.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY52179.1, ECO:0000313|Proteomes:UP000003089};
RN [1] {ECO:0000313|EMBL:EIY52179.1, ECO:0000313|Proteomes:UP000003089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY52179.1,
RC ECO:0000313|Proteomes:UP000003089};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY52179.1}.
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DR EMBL; AGXS01000015; EIY52179.1; -; Genomic_DNA.
DR AlphaFoldDB; I9GYF5; -.
DR STRING; 997884.HMPREF1068_01726; -.
DR PATRIC; fig|997884.3.peg.1757; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_006501_0_2_10; -.
DR Proteomes; UP000003089; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR048229; GalB-like.
DR InterPro; IPR040605; Glyco_hydro2_dom5.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR NCBIfam; NF041463; GalB; 1.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF18565; Glyco_hydro2_C5; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003089};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..840
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003720622"
FT DOMAIN 58..199
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 212..314
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 319..547
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 642..721
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT DOMAIN 734..836
FT /note="Glycoside hydrolase family 2"
FT /evidence="ECO:0000259|Pfam:PF18565"
SQ SEQUENCE 840 AA; 95535 MW; 6FF232B04AEBEDDD CRC64;
MKKSLFTAML ALFFLTHGQM IWAVDKTASV HTRYTFERGW KFIRSDDANF SLFDYDDSRW
QQVTVPHDWA IYGPFSIQND RQKVAIAQDG QKEAMEHAGR TGGLPFVGVG WYRLDFEAPA
FAKGKKATLV FDGAMSHARV YVNGKEAGYW PYGYNTFYLD VTPYLNAEGK NTLAVRLENE
VESSRWYPGA GLYRNVHLIV NEEAHIPMWG TQLTTPVVED NFARVHLNTS WVMPEGKSPS
SYRIVTEIKD ADGKVVSKES KQLTDFDNQI FSQEFVVEKP MLWTPDTPYL YIAESKVYEG
NTLKDESVTP FGIRSIEVIP DKGFFLNGKK TVFKGVCNHH DLGPLGAAVN DAAIRRQIRI
LKDMGCNAIR TSHNMPAPEL VKACDEMGMM LMVETFDEWK TAKCENGYHK EFDQWVEKDL
VNVLRHYRNH PSVVMWCVGN EVPDQWNGDR GPKLSRYLQD ICHREDPTRP VTQGMDAPDA
VINNNMAAVM DVAGFNYRPH KYQEAYKKLP QQIILGSETA STVSSRGIYK FPVTRTWMKK
YDDHQSSSYD VEHCGWSNLP EDDFIQHEDL PYCIGEFVWT GFDYLGEPTP YYTDWPSHSS
LFGIIDLAGL PKDRYYLYRS HWNKEKETLH ILPHWNWKGR EGEVTPVFVY TNYPSAELFI
NGKSQGKRTK DLSVTVYNSA DSVSMMSLKR QQRYRLMWMD TKYEPGTVKV VAYDENGKAV
AEKEIHTAGK PHHIELVPDR RMLQADGKDL CFVTVKVVDK DGNLCPEATD EIRFKVKGTG
VYCAGANGNP ASLESFQIPR MKVFSGMMTA VIQTTDKAGA IVLEATGSGL KKATLTVESK
//
