ID I9H539_9BACE Unreviewed; 447 AA.
AC I9H539;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=HMPREF1068_00387 {ECO:0000313|EMBL:EIY54674.1};
OS Bacteroides nordii CL02T12C05.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY54674.1, ECO:0000313|Proteomes:UP000003089};
RN [1] {ECO:0000313|EMBL:EIY54674.1, ECO:0000313|Proteomes:UP000003089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY54674.1,
RC ECO:0000313|Proteomes:UP000003089};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY54674.1}.
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DR EMBL; AGXS01000003; EIY54674.1; -; Genomic_DNA.
DR RefSeq; WP_007483223.1; NZ_JH724314.1.
DR AlphaFoldDB; I9H539; -.
DR STRING; 997884.HMPREF1068_00387; -.
DR GeneID; 69504427; -.
DR PATRIC; fig|997884.3.peg.405; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_2_0_10; -.
DR Proteomes; UP000003089; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000003089};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 46..157
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
FT REGION 383..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 51468 MW; CE853900765A05C9 CRC64;
MSEQFEMIAK TFQGLEEVLA EELIVLGAND VQIGRRMVSF SGDKEMMYKA NFCLRTAIRI
LKPIKHFKAK DADEVYEQIK AIAWEEILDV NKTFAVDAVV FSDEFRHSKF VSYKVKDAIV
DYFRELNGKR PSVRINRPDV LLNIHIAQTT CTLSLDSSGE SLHRRGYRQE AVEAPLNEVL
AAGMILMTGW RGECDLIDPM CGSGTIPVEA ALIARNIAPG VFRKEFAFEK WVDFDQDMFD
NLYNDDSQER EFTHKIYGYD NNPKANEIAT HNVKAAGVSK DIILKLQPFQ QFEQPAEKSI
IITNPPYGER ISTNDLLGLY SMIGERLKHA FVGNDAWVLS YREECFDQIG LKPSQKTPLF
NGALECEFRK YQIFDGKYKE FKGQEGEEEN KEGTPKEKRE FKPRREEGGR SFSSDRDRKP
REGRSFNGDR KPREFKKNWE PRGDKKE
//
