ID I9KXT8_LACPE Unreviewed; 553 AA.
AC I9KXT8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=phosphoenolpyruvate carboxykinase (ATP) {ECO:0000256|ARBA:ARBA00012363};
DE EC=4.1.1.49 {ECO:0000256|ARBA:ARBA00012363};
GN Name=pck {ECO:0000313|EMBL:EIW12666.1};
GN ORFNames=KCA1_2778 {ECO:0000313|EMBL:EIW12666.1};
OS Lactiplantibacillus pentosus KCA1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1136177 {ECO:0000313|EMBL:EIW12666.1};
RN [1] {ECO:0000313|EMBL:EIW12666.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCA1 {ECO:0000313|EMBL:EIW12666.1};
RX PubMed=23527145;
RA Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B.,
RA van Hijum S.A., Siezen R.J.;
RT "Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a
RT Healthy Premenopausal Woman.";
RL PLoS ONE 8:E59239-E59239(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC EC=4.1.1.49; Evidence={ECO:0000256|ARBA:ARBA00001389};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC family. {ECO:0000256|ARBA:ARBA00006052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIW12666.1}.
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DR EMBL; AKAO01000082; EIW12666.1; -; Genomic_DNA.
DR RefSeq; WP_003639985.1; NZ_CM001538.1.
DR AlphaFoldDB; I9KXT8; -.
DR PATRIC; fig|1136177.4.peg.2838; -.
DR eggNOG; COG1866; Bacteria.
DR HOGENOM; CLU_037428_0_0_9; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000005826; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.228.20; -; 1.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR Pfam; PF01293; PEPCK_ATP; 1.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:EIW12666.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:EIW12666.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000313|EMBL:EIW12666.1};
KW Transferase {ECO:0000313|EMBL:EIW12666.1}.
SQ SEQUENCE 553 AA; 61826 MW; D70B50F5C7D59E5F CRC64;
MSTKNSYQLA DIGRHNPIFS QIRSTVETAF YGNNMHQVAD VADAYHRATK DPGTVITDLP
IYRATDLGLP EDAKMLIANT GKVVGRTAQA RRILGNPGVS EADMAGRLRQ AIFASAHQDF
IKTDVLVGLD EDFIVRAHLA IPDGFANNLL SYMLNFQPIT AAYQAMFERS VAYPEGDIYI
YADPTYHDPD YPDGLAIFDP QHNTAAILGM PYFGELKKST LTLAWSIAHR HGFVACHGGL
KAFHFKDKQD QVFAMFGLSG SGKSTLTHAK HGYKYDITVL HDDAFVINRQ NGSSVALEPS
YFDKTNDYPM TSDETKYFMT IQNVGVTLDD QGRKVLVTED LRNGNGRTIK SRYASTNRVD
KEDAPINAIF WIMKDDSLPP VIKVDDPVLA ATFGATLATK RSSAENIIGD VDRNALVIEP
FANPFRVYPL SEDYHDFKAL FEERHLNCYL LNTGYFGDKK VPKEITLGAL EAIVNNTTEW
ESFAGLDHMQ NLKLTDFPVD GENADYRQLV ATRLGIRANF VDQYEHNNND RLPHEVTDSL
IHLQQQLKQP LAK
//
