ID I9KYJ8_LACPE Unreviewed; 431 AA.
AC I9KYJ8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Glycoside hydrolase family 43 {ECO:0000313|EMBL:EIW13054.1};
GN ORFNames=KCA1_2347 {ECO:0000313|EMBL:EIW13054.1};
OS Lactiplantibacillus pentosus KCA1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1136177 {ECO:0000313|EMBL:EIW13054.1};
RN [1] {ECO:0000313|EMBL:EIW13054.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCA1 {ECO:0000313|EMBL:EIW13054.1};
RX PubMed=23527145;
RA Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B.,
RA van Hijum S.A., Siezen R.J.;
RT "Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a
RT Healthy Premenopausal Woman.";
RL PLoS ONE 8:E59239-E59239(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIW13054.1}.
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DR EMBL; AKAO01000072; EIW13054.1; -; Genomic_DNA.
DR RefSeq; WP_003639562.1; NZ_CM001538.1.
DR AlphaFoldDB; I9KYJ8; -.
DR PATRIC; fig|1136177.4.peg.2304; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_009397_11_4_9; -.
DR Proteomes; UP000005826; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd04084; CBM6_xylanase-like; 1.
DR CDD; cd18620; GH43_XylA-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR005084; CMB_fam6.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772:SF2; BETA-1,4-XYLOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF03422; CBM_6; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT DOMAIN 323..425
FT /note="CBM6"
FT /evidence="ECO:0000259|Pfam:PF03422"
FT SITE 126
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 431 AA; 48287 MW; 6BF43A8226E8E818 CRC64;
MNPVLKSNNY IPDVEARAMP DGKVYLYGSR DNAGDTEFCS TQYQTFSSKD LVHWDDEGVI
FDSTEEQYGI NNGLTLGAPD CVYYEGNYYL YYCMYGNHMG VAVSNSPAGP FKNLGHVVPA
DGQSIDPAVL VDDDGSCYYF WGQFSLQGGK LDKDMKTVIP ETITSNILTE HEQGFHEGAS
IRKINGIYYL TYTDISRGRA SCLAYATAKS PLGPYQKRGI IIDNTGCDSG DWNNHGSIEM
IHGKPYVFYH RSSQNSIYNR RVCIEPLSMD DHGNIAEVPM TSNGVEDHFP INMPVNVRHL
SRMRLKLPFD SLIQPMSLMP SHDSEILAYT RNQDWVQFDR IDLGYNCQAV EISAASPKPM
IVEFWIENNC KIGQVVVDAT GSDWHNYQTF SGQIKATSGI HTVWLRIVAN NNAVGRLGNI
ENFCFRGQAN E
//
