ID IACX1_WHEAT Reviewed; 121 AA.
AC Q43723;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=Trypsin/alpha-amylase inhibitor CMX1/CMX3;
DE AltName: Full=ITRL-1/ITRL-3;
DE Flags: Precursor;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Chinese Spring; TISSUE=Endosperm;
RX PubMed=7811982; DOI=10.1007/bf00040705;
RA Sanchez de la Hoz P., Castagnaro A., Carbonero P.;
RT "Sharp divergence between wheat and barley at loci encoding novel members
RT of the trypsin/alpha-amylase inhibitors family.";
RL Plant Mol. Biol. 26:1231-1236(1994).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the protease inhibitor I6 (cereal trypsin/alpha-
CC amylase inhibitor) family. {ECO:0000305}.
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DR EMBL; X75610; CAA53282.1; -; mRNA.
DR EMBL; X75608; CAA53280.1; -; mRNA.
DR PIR; S51810; S51810.
DR AlphaFoldDB; Q43723; -.
DR SMR; Q43723; -.
DR STRING; 4565.Q43723; -.
DR Allergome; 11042; Tri a CMX.
DR Proteomes; UP000019116; Unplaced.
DR ExpressionAtlas; Q43723; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd00261; AAI_SS; 1.
DR Gene3D; 1.10.110.10; Plant lipid-transfer and hydrophobic proteins; 1.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR PANTHER; PTHR34481; TRYPSIN/FACTOR XIIA INHIBITOR-RELATED; 1.
DR PANTHER; PTHR34481:SF15; TRYPSIN_ALPHA-AMYLASE INHIBITOR CMX1_CMX3; 1.
DR Pfam; PF00234; Tryp_alpha_amyl; 1.
DR SUPFAM; SSF47699; Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin; 1.
PE 2: Evidence at transcript level;
KW Protease inhibitor; Reference proteome; Secreted;
KW Serine protease inhibitor; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..121
FT /note="Trypsin/alpha-amylase inhibitor CMX1/CMX3"
FT /id="PRO_0000014348"
SQ SEQUENCE 121 AA; 13831 MW; 56A01241918CEFF5 CRC64;
MAFKHQLILS TAILLAVLAA ASASFREQCV PGREITYESL NARREYAVRQ TCGYYLSAER
QKRRCCDELS KVPELCWCEV LRILMDRRVT KEGVVKGSLL QDMSRCKKLT REFIAGIVGR
E
//
