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Database: UniProt
Entry: J0RK19_BARTA
LinkDB: J0RK19_BARTA
Original site: J0RK19_BARTA 
ID   J0RK19_BARTA            Unreviewed;       543 AA.
AC   J0RK19;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   05-JUN-2019, entry version 43.
DE   RecName: Full=Transcription termination/antitermination protein NusA {ECO:0000256|HAMAP-Rule:MF_00945};
GN   Name=nusA {ECO:0000256|HAMAP-Rule:MF_00945};
GN   ORFNames=ME9_00508 {ECO:0000313|EMBL:EJF96359.1};
OS   Bartonella taylorii 8TBB.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bartonellaceae; Bartonella.
OX   NCBI_TaxID=1094560 {ECO:0000313|EMBL:EJF96359.1, ECO:0000313|Proteomes:UP000002648};
RN   [1] {ECO:0000313|EMBL:EJF96359.1, ECO:0000313|Proteomes:UP000002648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8TBB {ECO:0000313|EMBL:EJF96359.1,
RC   ECO:0000313|Proteomes:UP000002648};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Kirby J., Kosoy M., Birtles R., Probert W.S.,
RA   Chiaraviglio L., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA   Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA   McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Bartonella taylorii 8TBB.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in both transcription termination and
CC       antitermination. {ECO:0000256|HAMAP-Rule:MF_00945}.
CC   -!- SUBUNIT: Monomer. Binds directly to the core enzyme of the DNA-
CC       dependent RNA polymerase and to nascent RNA. {ECO:0000256|HAMAP-
CC       Rule:MF_00945}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00945}.
CC   -!- SIMILARITY: Belongs to the NusA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00945}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJF96359.1}.
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DR   EMBL; AIMD01000020; EJF96359.1; -; Genomic_DNA.
DR   RefSeq; WP_004858648.1; NZ_JH725050.1.
DR   STRING; 1094560.ME9_00508; -.
DR   EnsemblBacteria; EJF96359; EJF96359; ME9_00508.
DR   PATRIC; fig|1094560.3.peg.560; -.
DR   OrthoDB; 384865at2; -.
DR   Proteomes; UP000002648; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1480.10; -; 1.
DR   Gene3D; 3.30.300.20; -; 2.
DR   HAMAP; MF_00945_B; NusA_B; 1.
DR   InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR015946; KH_dom-like_a/b.
DR   InterPro; IPR025249; KH_dom_NusA-like.
DR   InterPro; IPR009019; KH_sf_prok-type.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR030842; NusA_bac.
DR   InterPro; IPR036555; NusA_N_sf.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   InterPro; IPR013735; TF_NusA_N.
DR   InterPro; IPR010214; Tscrpt_termin_fac_NusA_C_rpt.
DR   InterPro; IPR010213; Tscrpt_termination_fac_NusA.
DR   PANTHER; PTHR22648; PTHR22648; 1.
DR   Pfam; PF13184; KH_5; 1.
DR   Pfam; PF08529; NusA_N; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00322; KH; 2.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF47794; SSF47794; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF54814; SSF54814; 2.
DR   SUPFAM; SSF69705; SSF69705; 1.
DR   TIGRFAMs; TIGR01953; NusA; 1.
DR   TIGRFAMs; TIGR01954; nusA_Cterm_rpt; 1.
DR   PROSITE; PS50126; S1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002648};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00945};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00945};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00945};
KW   Transcription antitermination {ECO:0000256|HAMAP-Rule:MF_00945};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00945};
KW   Transcription termination {ECO:0000256|HAMAP-Rule:MF_00945}.
FT   DOMAIN      140    204       S1 motif. {ECO:0000259|PROSITE:PS50126}.
FT   REGION      522    543       Disordered. {ECO:0000256|MobiDB-lite:
FT                                J0RK19}.
FT   COILED      407    431       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   543 AA;  60484 MW;  706C052E7DE70B6C CRC64;
     MATSANRLEI LQIADAVARE KSIDRDIVIS AMADAIQKAA RSRYGQETNI RAEINSKTGE
     IKLQRLLKIV DVVEDYTTEI TLSDALKRQA DAKIGDFFAD LLPPMDFGRI AAQSAKQVIV
     QRVRDAERDQ QYEEFKNKIG EIISGTVKRV EYGNVIVDLG RGEAIVRRDE LIPRESFRYG
     DRIRAYVNDV HRESRGPQIF LSRTHPQFMV KLFTMEVPEI YDGIIEIKSV ARDPGSRAKI
     AVVSRDGSID PVGACVGMRG SRVQAVVAEL QGEKIDIIPW SPDAATFIVN ALQPAEVSKV
     VLDEDAERIE VIVPDDQLSL AIGRRGQNVR LASQLTGWNI DILTEQEESE NRQKEFTERS
     KLFMESLDVD EIIGQVMASE GFSSIEEIAY IDLEEIASID GFDHETAAEI QNRAREYLEH
     KEKELDEKRK KLGVSDELRA LPGMTSAMLV AVGEDGVKTI EDFAGYAVDD LAGWRERKEG
     QTQNFSGILT PFDITRADAE AMVLAARVQA GWIDQADLVT ETPAESGNSA KNEKIDNLNV
     DTI
//
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