ID   J0RWE4_9FLAO            Unreviewed;       770 AA.
AC   J0RWE4;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=FF52_16893 {ECO:0000313|EMBL:EJG00075.1};
OS   Flavobacterium sp. F52.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=1202532 {ECO:0000313|EMBL:EJG00075.1, ECO:0000313|Proteomes:UP000002690};
RN   [1] {ECO:0000313|EMBL:EJG00075.1, ECO:0000313|Proteomes:UP000002690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F52 {ECO:0000313|EMBL:EJG00075.1,
RC   ECO:0000313|Proteomes:UP000002690};
RX   PubMed=22965088; DOI=10.1128/JB.01249-12;
RA   Kolton M., Green S.J., Harel Y.M., Sela N., Elad Y., Cytryn E.;
RT   "Draft Genome Sequence of Flavobacterium sp. Strain F52, Isolated from the
RT   Rhizosphere of Bell Pepper (Capsicum annuum L. cv. Maccabi).";
RL   J. Bacteriol. 194:5462-5463(2012).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJG00075.1}.
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DR   EMBL; AKZQ01000034; EJG00075.1; -; Genomic_DNA.
DR   RefSeq; WP_008467424.1; NZ_AKZQ01000034.1.
DR   AlphaFoldDB; J0RWE4; -.
DR   PATRIC; fig|1202532.3.peg.3458; -.
DR   eggNOG; COG3525; Bacteria.
DR   OrthoDB; 9763537at2; -.
DR   Proteomes; UP000002690; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR026876; Fn3_assoc_repeat.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF13287; Fn3_assoc; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..770
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003738722"
FT   DOMAIN          28..157
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          161..510
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        341
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   770 AA;  87172 MW;  89D34FD654166BDB CRC64;
     MKKLVFLLTL ISSIFSAKAQ KVYTESDIRI IPKPTQTLIK TGVFEFTKDT KFVVNGDFQK
     DVANALASKF GTAAGWKPEV TAKAPASNYV LLKTDPNLKN EAYVLDVNPT NIVISAKGNN
     GFLYALESIR QLLPEAIESK FAITSAKWQI PSLTINDEPR FKWRGLMLDF SRHFFDKNYV
     LATIDRLAAH KMNVLHMHLV DDQGWRIEIK KYPKLTEVGA WRVDQENRSW NARLTTNPDE
     KGTYGGFFTQ EELKEIVKYA ATKGIEVIPE IEMPAHVSSA IAAYPELACF NQRIGVPSGG
     VWPITDIYCA GKETTFEFLQ NVIDEVITIF PSKYIHIGGD EATKTNWTKC PYCQKRIKDE
     RLKNVDELQS YFVKRMEKYI NSKGKKVIGW DEILEGGLAP DATVMSWRGM KGGIEAADQG
     HDVIMTPETP CYFNFYQGPQ NEEPLAFDAY NPLSEVYKFD PVVSTMTPQE AAHVLGGQAN
     LWAEYITGPK DSEYMIFPRL AALSETLWSP KEKRNWNDFT SRLFSMFKRY DYQGLNYAKS
     AYLVTASSTA DLANKQIKVE LKNEFPNPDI RYVLGNQSIE HHAIRYTSPI EIKETTVLKA
     SLFQDEKPAG KTFTDTIVFH KGFAKKVKYL TPYNENYKGD ANTMVNTIRG SKNFHDGQWQ
     AWLVNDMELV IDLEKIESIE QVSVGALESQ GAGVNFPIQI KVLISTDGIK YTQVGKITRP
     YAANPVPELK DFKINFQKQN VRFVKVIGGN LKKSPKGESS WLFVDEILVN
//