ID J0S1C4_9EURY Unreviewed; 573 AA.
AC J0S1C4;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
GN ORFNames=Metli_1737 {ECO:0000313|EMBL:EJG07681.1};
OS Methanofollis liminatans DSM 4140.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanofollis.
OX NCBI_TaxID=28892 {ECO:0000313|EMBL:EJG07681.1};
RN [1] {ECO:0000313|EMBL:EJG07681.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4140 {ECO:0000313|EMBL:EJG07681.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Lu M., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schuler E., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanofollis liminatans DSM 4140.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR EMBL; CM001555; EJG07681.1; -; Genomic_DNA.
DR RefSeq; WP_004039496.1; NZ_CM001555.1.
DR AlphaFoldDB; J0S1C4; -.
DR STRING; 28892.Metli_1737; -.
DR PATRIC; fig|28892.9.peg.1890; -.
DR HOGENOM; CLU_015515_1_0_2; -.
DR OrthoDB; 6113at2157; -.
DR Proteomes; UP000005095; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR CDD; cd00858; GlyRS_anticodon; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:EJG07681.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 6..463
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 573 AA; 64743 MW; 2D987DBE6C1D7C18 CRC64;
MSDTYDKVIE LAKRRGFVWP SAEVYGAVAG FIDYGPLGAM MKRRVEEIWR HYYVIREGYY
EIECPTVGTE SIYIASGHVK GFADKMCECP HCHEYFRADH LAEACGIASA SHLTREELAA
AIEEVACPGC GEVFGKTEVF DFNLMFQTTI GPGSQRKGYL RPETAQGIFT DFSRLSRFYR
MKLPFGAVQI GKSYRNEISP RQGMIRLREF TQAEAEIFVN PESKRHPNFG RYADYAVDLW
GIEQQQQNTD PVSKTMREAV DEGIIANEYI AYYLALTHDL LTSIGIDRNR LRFRQHLPDE
RAHYAIDCWD AEVRSERFGW VETVGIADRT DYDLRAHSGE SGDTMTVFVP FDEARTEKRK
RIVADMGVLG PKYRGKAKKI ADALAETSPG PDGAEVTVDG ETFFIPGDLY TVHEEEVEVR
GAEVMPHVIE PSYGIDRMIY GVLEHSYDEE IVEGEERRVL RLPACIAPVQ VAVFPLVNKD
GLEEIARTIT SDLQDARILA DYDDNGAIGR RYRRQDEVGT PFAVTVDYET KETGTVTLRD
RDSMEQVRIP AGDLVATIGS LIRCRTAFAD LKQ
//
