ID   J0UUS8_9LACO            Unreviewed;       756 AA.
AC   J0UUS8;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:KRN09932.1};
GN   ORFNames=FD00_GL000559 {ECO:0000313|EMBL:KRN09932.1};
OS   Liquorilactobacillus mali KCTC 3596 = DSM 20444.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Liquorilactobacillus.
OX   NCBI_TaxID=1046596 {ECO:0000313|EMBL:KRN09932.1, ECO:0000313|Proteomes:UP000050898};
RN   [1] {ECO:0000313|EMBL:KRN09932.1, ECO:0000313|Proteomes:UP000050898}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20444 {ECO:0000313|EMBL:KRN09932.1,
RC   ECO:0000313|Proteomes:UP000050898};
RX   PubMed=26415554; DOI=10.1038/ncomms9322;
RA   Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA   Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA   Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA   Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA   de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA   Zhang H., O'Toole P.W.;
RT   "Expanding the biotechnology potential of lactobacilli through comparative
RT   genomics of 213 strains and associated genera.";
RL   Nat. Commun. 6:8322-8322(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRN09932.1}.
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DR   EMBL; AYYH01000016; KRN09932.1; -; Genomic_DNA.
DR   RefSeq; WP_003687197.1; NZ_BACP01000068.1.
DR   AlphaFoldDB; J0UUS8; -.
DR   PATRIC; fig|1046596.6.peg.600; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000050898; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR048228; HelD_bacillota.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   NCBIfam; NF041464; HelD_BACSU; 1.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          208..587
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         229..236
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   756 AA;  86854 MW;  D01FE3F6A5030A17 CRC64;
     MGKERNFEQK RVDTVVGKIE KSLLKTQHEY DKARTERSSV EKNYVQNAKI NTFEVDDQME
     TNAEVQQQKQ LIAKNVETEK ILSRQIHLLS DLEDSPYFGR IDIHEKGETS PETLYIGTSS
     FNDDMGNFLI YDWRAPISSI YYNGTLGTVS YTTPIGEQEA QLLKKRQFRI QAGKITNMFD
     TNETVGDELL QEMLGEQSDE YMKNIVATIQ KEQNDIIRDT THDLLIVQGV AGSGKTSAIL
     QRIAFLLYHS RSELSAEQIV LFSPNLLFSH YISEVLPSLG ERNMRQVTLA EFFAQRFEGL
     KVETLFDNFE KKSSSSVNTE ITVKEDADFM RTIKEYVTNL DSSHIFFNDL ILVDQVIFSS
     SEIRSLYSKL PVAQPHHIRH FELKNILIKE LKKKIKKELN AQWVLKKIDS LTEEEYYSLL
     GNYQRGRFED IEAEINYLSN KIVSAKFEPI YEAIYNNYFI DVYHQYSEFL KEVLSDDVVR
     FNNELEYHRI RLEDCAPILY LRDQITGEGQ NHSIQHLFID EMQDYSLAQI YYLHAAFPNA
     HLTLLGDSEQ ALYHEIQAPQ ELMKDLKQTI NPKRARMIEL NKSYRSTFEI TSFMKALLPD
     GDKIQAFTRS GSLPKLVLTD ESNTISKLLT EARLLLKKNE TVAIITKDVA TCQVLLKSFK
     TKDAPTLITN NDRSLPKGLV LLPIYLAKGL EFDAVIAFEV SQNNFADDSS RGVLYTICSR
     AMHDLVLISV KGISNLITAI PSGLFTIEQD ITFKQK
//