ID J0XCL6_9ACTO Unreviewed; 446 AA.
AC J0XCL6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein {ECO:0000313|EMBL:EJF46441.1};
GN ORFNames=HMPREF1318_2711 {ECO:0000313|EMBL:EJF46441.1};
OS Actinomyces massiliensis F0489.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1125718 {ECO:0000313|EMBL:EJF46441.1, ECO:0000313|Proteomes:UP000002941};
RN [1] {ECO:0000313|EMBL:EJF46441.1, ECO:0000313|Proteomes:UP000002941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0489 {ECO:0000313|EMBL:EJF46441.1,
RC ECO:0000313|Proteomes:UP000002941};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJF46441.1}.
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DR EMBL; AKFT01000063; EJF46441.1; -; Genomic_DNA.
DR RefSeq; WP_008730659.1; NZ_AKFT01000063.1.
DR AlphaFoldDB; J0XCL6; -.
DR PATRIC; fig|1125718.3.peg.892; -.
DR eggNOG; COG1301; Bacteria.
DR OrthoDB; 9768885at2; -.
DR Proteomes; UP000002941; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF9; INTEGRAL MEMBRANE TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002941};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 52..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 446 AA; 46539 MW; 6252D940ECEB06ED CRC64;
MSYLRRALSA SGILVWVLAA IVLALVLGSI KIGGSPFIPQ AAGRIFATFS DLFSQFLSFA
IPLIIIGLVT PAIADLGRGA GKWLGITTAI AYASTLFSGF LTYVVCAGFL PRLLAGTALS
DVEEPGSALE TYFSIEMPAP VPVMTALLLS FVLGIGLSMV PRGVLRKGFI EFRAIITRLI
ERIIIPLLPL HIFGIFLNLT YTGEAWSVMR ALMRVVVVVL VLEVVILGVQ YVVAGFIGGK
NPVRAVVTMM PAYLTALGTS SSAATIPVTL AQTKKNGVSD AVASFTVPLC ATIHLAGSTS
KIFAFAFAIV LTQGLSVSTV QWVGFIFMLG ITMVAAPGVP GGAIMAATGL LSSMLGFDEA
QVALMIATYI AMDSFGTATN VTGDGAIAIV IDRLAGGQIR DDGDPENARE LSFDGMKYLD
RVSVEGVVSP EELVSSAETA GADAAS
//
