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Database: UniProt
Entry: J0YPM4_9STRE
LinkDB: J0YPM4_9STRE
Original site: J0YPM4_9STRE 
ID   J0YPM4_9STRE            Unreviewed;       343 AA.
AC   J0YPM4;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   08-MAY-2019, entry version 31.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SPAR10_0264 {ECO:0000313|EMBL:EJG89401.1};
OS   Streptococcus infantis SPAR10.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1159208 {ECO:0000313|EMBL:EJG89401.1, ECO:0000313|Proteomes:UP000010312};
RN   [1] {ECO:0000313|EMBL:EJG89401.1, ECO:0000313|Proteomes:UP000010312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SPAR10 {ECO:0000313|EMBL:EJG89401.1,
RC   ECO:0000313|Proteomes:UP000010312};
RA   Chancey S., Kumar N., Sengamalay N., Matthews C., Hine E.,
RA   Pallavajjal A., Abolude O., Daugherty S.C., Parankush S.P.,
RA   Sadzewicz L., Tallon L.J., Farley M.M., Baughman W., McGee L.,
RA   Stephens D.S., Tettelin H.;
RT   "Genomic Sequence of Streptococcus mitis SPAR10.";
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJG89401.1}.
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DR   EMBL; ALCH01000001; EJG89401.1; -; Genomic_DNA.
DR   RefSeq; WP_004250797.1; NZ_ALCH01000001.1.
DR   EnsemblBacteria; EJG89401; EJG89401; SPAR10_0264.
DR   PATRIC; fig|1159208.3.peg.256; -.
DR   BioCyc; SMIT1159208:G129M-976-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000010312; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000010312};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:EJG89401.1}.
FT   DOMAIN       34    333       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   343 AA;  38545 MW;  6532EE27BD8B2802 CRC64;
     MAFIEKGQEI DIEAIKAETR LSAEALQYKE SRDQELADIL SGKDDRVLLV IGPCSSDNEE
     AVLEYARRLA DLQKKVADKI FMVMRVYTAK PRTNGDGYKG LVHQPDTSKA PSLINGLQAV
     RQLHYRVITE TGLTTADEML YPANLVLVDD LVSYHAVGAR SVEDQEHRFV ASGIDAPVGM
     KNPTSGNLSV MFNAIYAAQN KQTFLFHGQE VETSGNPLAH VILRGALNEY GKNEPNFYYE
     TLLDAIGRYE SMGLENPFIM IDTNHDNSGK QYMEQVRIVR QTLLNRAWNE KIKKTIRGFM
     IESYLADGRQ NQPEIFGRSI TDPCLGWENT VALVEEIYST LTK
//
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