ID   J1EA24_9BURK            Unreviewed;       699 AA.
AC   J1EA24;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Putative transmembrane sensor domain protein {ECO:0000313|EMBL:EJE49276.1};
GN   ORFNames=PMI14_06170 {ECO:0000313|EMBL:EJE49276.1};
OS   Acidovorax sp. CF316.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax.
OX   NCBI_TaxID=1144317 {ECO:0000313|EMBL:EJE49276.1, ECO:0000313|Proteomes:UP000004811};
RN   [1] {ECO:0000313|EMBL:EJE49276.1, ECO:0000313|Proteomes:UP000004811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF316 {ECO:0000313|EMBL:EJE49276.1,
RC   ECO:0000313|Proteomes:UP000004811};
RX   PubMed=23045501; DOI=10.1128/JB.01243-12;
RA   Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA   Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT   "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT   sequences from diverse bacteria isolated from the rhizosphere and
RT   endosphere of Populus deltoides.";
RL   J. Bacteriol. 194:5991-5993(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJE49276.1}.
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DR   EMBL; AKJX01000252; EJE49276.1; -; Genomic_DNA.
DR   AlphaFoldDB; J1EA24; -.
DR   PATRIC; fig|1144317.3.peg.5689; -.
DR   Proteomes; UP000004811; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004811};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EJE49276.1};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..699
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003741903"
FT   TRANSMEM        331..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        403..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          468..611
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          678..699
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  73349 MW;  B267800C59DFAB8C CRC64;
     MAAAAIVSLL LSLLFGPALQ AVEERVGDWV WRLGSQKTEE RRVLVVDIDE KSLAEVGPWP
     WPRSTQARLI EQIAQMGARE QILDVVFTDP RDDDASLLAA VAEHRPVLAQ VFALGASGPG
     TGLPQLSEQA APRVGQPAGA LDWASCPAPF SEALGHLSNF PALAALGDMP QGRTGHISPR
     IADDGVVRHQ PAIICWQGKS YPSLAIASLL RATSETSLLL QRGGWWDAPW TLGSAGQALP
     ALPLDERGNM RVAWRLHPDS FVSIPAADVL AGRVPTDIMT GAWVLVGASA FGMNDTIATP
     YSGASAGLLA HAQILSALVD GHTPYTPRAA LPLQAIAAAL GALLLWLLVR LAGQGGAAVR
     DAQAPTPSPM LRMPVYLLPV AALAYALALV VAHALALWLA DVWVGWLLPA VFVLLAGVFA
     GTIEHARSRS ERDRLYQHLA SYLPAPVAAA LALQPPSSAI RASTRQVSVL LADIRNFSAY
     CEARPPEEAA AVLHAFFSAA SRIVQAHGGV IESFQGDAVV AVWNGADDVP PPSTADDQHA
     QVHSRQAVAA ALDLLTESFK LLPDPAPAGL EPLSLGLGLE TGPAMVGSFG LASRRTHTVM
     GRTITIASRL VDLTVDLAHP ILVGEGMAAQ LGGQFSLGAR ADGRGAPETQ HLQSMGTFLL
     EGLRVPHHIY AVPLDTLAAE HPPEPGDSQA AQLTAHGTA
//