ID J1GXN0_9ACTO Unreviewed; 419 AA.
AC J1GXN0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF1318_2819 {ECO:0000313|EMBL:EJF37880.1};
OS Actinomyces massiliensis F0489.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1125718 {ECO:0000313|EMBL:EJF37880.1, ECO:0000313|Proteomes:UP000002941};
RN [1] {ECO:0000313|EMBL:EJF37880.1, ECO:0000313|Proteomes:UP000002941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0489 {ECO:0000313|EMBL:EJF37880.1,
RC ECO:0000313|Proteomes:UP000002941};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJF37880.1}.
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DR EMBL; AKFT01000199; EJF37880.1; -; Genomic_DNA.
DR RefSeq; WP_008733298.1; NZ_AKFT01000199.1.
DR AlphaFoldDB; J1GXN0; -.
DR PATRIC; fig|1125718.3.peg.2552; -.
DR eggNOG; COG1472; Bacteria.
DR Proteomes; UP000002941; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF15; BETA-HEXOSAMINIDASE LPQI; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EJF37880.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002941}.
FT DOMAIN 85..415
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT REGION 35..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 419 AA; 42652 MW; 434B97852A45FC21 CRC64;
MDDHSSASPS PSIAHRALRR RPVVLTGLLG VASLAGCGSL SSKPRPASTD DPGTMSPTAA
PEDFSTESAP AASASATPNP LDGWTLEQKV GQLLMVGADT SGPQMVSIDA VATHHVGNVF
IARQTRSGAD SVRGVITALT DLVGSETTHD TPLLVATDQE GGQVQVLGGS GFSDIPSASE
QAIMSTDDLT ASARTWGQEL ADVGVTMNLA PVADLVDIPD PSSNAPIGRW GREYGRSATT
SLDRATAFAR GMEAAGVIPT YKHFPGLGRV TANTDTADGV TDSITTRSGD PAVSVFAEAI
TGGARVIMVS SAIYSAIDSS APATFSSVVV TDMLRGDLGF TGVVITDDVS AAVQVDAWTP
AERAVQAVKA GCDIVLASAD ATMAADMAEA LIAEAQADPA FAQRVDESAT RVISLKAGS
//
