ID J1RHG5_9ACTN Unreviewed; 338 AA.
AC J1RHG5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:EJJ03789.1};
GN ORFNames=SU9_001565 {ECO:0000313|EMBL:QTZ90304.1}, SU9_26699
GN {ECO:0000313|EMBL:EJJ03789.1};
OS Streptomyces auratus AGR0001.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ03789.1};
RN [1] {ECO:0000313|EMBL:EJJ03789.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ03789.1};
RX PubMed=22965094; DOI=10.1128/JB.01155-12;
RA Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT Producing Actinomycete.";
RL J. Bacteriol. 194:5472-5473(2012).
RN [2] {ECO:0000313|EMBL:QTZ90304.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AGR0001 {ECO:0000313|EMBL:QTZ90304.1};
RA Wen M.-L., Han X.-L., Xiong J.;
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJGV01000169; EJJ03789.1; -; Genomic_DNA.
DR EMBL; CP072931; QTZ90304.1; -; Genomic_DNA.
DR RefSeq; WP_006606848.1; NZ_CP072931.1.
DR AlphaFoldDB; J1RHG5; -.
DR STRING; 1160718.SU9_26699; -.
DR KEGG; sauh:SU9_001565; -.
DR PATRIC; fig|1160718.3.peg.5408; -.
DR eggNOG; COG2130; Bacteria.
DR HOGENOM; CLU_026673_29_2_11; -.
DR Proteomes; UP000009036; Chromosome.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009036}.
FT DOMAIN 21..334
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 338 AA; 35065 MW; 8CCF25C436175F0C CRC64;
MTVPSTGTEV RLAARPEGWP TAENFSVVQA EPPAVRTGQV LIRNLVMSVD PYMRGRMNKT
RSYVPPFAVG KALDGGAVGE VVVSKSSHLA VGDLVLHGLG WREYAVVGAA GAVRIDPALA
PPGAYLGVLG MPGHAAYTGL LKVAEFRPGD TVFVSGAAGA VGSLVGQIAR LCGAERVIGS
AGSAEKVAYL TGELGFDAAF DYKDGPVLEQ LAKAAPAGID VYFDNVGGDH LDAALVLARM
GARFALCGSI SQANEQAPPA GPRNLTQAIA KGLTLRGFLV GGHADLPDEF TARMGGWLAD
GRISYRETVV RGLENAPTAF IDMLRGANTG KMLVRIAE
//
