ID   J1RU80_9ACTN            Unreviewed;      1033 AA.
AC   J1RU80;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   SubName: Full=GCN5-related N-acetyltransferase {ECO:0000313|EMBL:EJJ08074.1};
GN   ORFNames=SU9_05331 {ECO:0000313|EMBL:EJJ08074.1};
OS   Streptomyces auratus AGR0001.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ08074.1};
RN   [1] {ECO:0000313|EMBL:EJJ08074.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ08074.1};
RX   PubMed=22965094; DOI=10.1128/JB.01155-12;
RA   Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT   "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT   Producing Actinomycete.";
RL   J. Bacteriol. 194:5472-5473(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJJ08074.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJGV01000042; EJJ08074.1; -; Genomic_DNA.
DR   AlphaFoldDB; J1RU80; -.
DR   STRING; 1160718.SU9_05331; -.
DR   PATRIC; fig|1160718.3.peg.1096; -.
DR   eggNOG; COG0456; Bacteria.
DR   eggNOG; COG1042; Bacteria.
DR   HOGENOM; CLU_007415_3_0_11; -.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13380; CoA_binding_2; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000313|EMBL:EJJ08074.1}.
FT   DOMAIN          56..216
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          659..743
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        660..741
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1033 AA;  109372 MW;  E7BD7149BA5E3C60 CRC64;
     MPYGLHGSPG LLCIPSVRAP PVVGARSYAV RMQKSQDHAY PAHWEADVVL RDGGTARIRP
     ITPDDAERLV SFYEQVSDES KYYRFFAPYP RLSARDVHRF THHDYVDRVG LAATVGGEFI
     ATVRYDRIDD QGLPAKDPED DQAEVAFLVQ DAHQGRGVAS ALLEHIAAVA RERGIRRFAA
     EVLPANSKMI KVFTDAGYTH KRTFEDGVVR LEFDLEPTEQ SMAVMRGREQ RAEARSVQRL
     LTPRSVAVIG TGRAPGGVGR TALRSLLDSG FTGRVHAVNR AFPEGMQRLD PEGVPAVRAL
     REISDPVDLA VIAVPADSVP DVVRDCGEHG VQGVLILSSG YAEAGPDGRE RQRDLLRQAR
     SYGMRLIGPN AFGLINTAPD VRLNASLAPQ MPGAGHIGLF TQSGAIGIAL LSGLHARGPG
     DGGIAGISAF VSAGNRADVS GNDLLQYWYE DPDTDVVILY LESIGNPRKF ARLARRTAAV
     KPVVVARGAR HNGTAPPGHA VPTVRVPDST VAALMRQAGV IRVDTVTELI DAGLLLASQP
     LPAGSRIAIL GNSESLALLA YDACLTERLR PQRPHVLTSA ATPDDFRAAL AEALAGDGCD
     AVVVTAIPWV GEGAAVSTGG GEGAALAAAL RTAAEAHPEK PVAVVHLAMN ELAETLAAPA
     PAPAPAPASG PDAPARARPP RPEDPAPAPA RPPESAPPPR SPSYPARPLS PPGPPPTLVA
     PQPAPARDPG TTPPPRRAAP LRIPAYPAAE RAVRALAEAV RYAAWRREAA DPGRVPEYDD
     IQETAAGADI ERLLGRLTLD VPTGRSVPVP PEDAEALLAR YGIHTRPVLA APDPDTAVRA
     AARLGYPVAL KTTAPHLRHR ADLGGVRLDI AGERELRRTY AELTDFLGSP EELRPVVQSM
     VPRGVDTVIR AAIDPAAGAV LSFGLAGAPS QLLGDIAHRL IPATDREVAE QIRSIRAAPL
     LFGWRGSQPV DTAALAELLL RVSRLVDDHP EVVAVDLEPV VVAAHGLSVL GASVRLARPP
     ATTDLGPRRL PVY
//