ID J1ZNL2_9ACTN Unreviewed; 304 AA.
AC J1ZNL2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:EJJ03086.1};
GN ORFNames=SU9_005895 {ECO:0000313|EMBL:QTZ95935.1}, SU9_30494
GN {ECO:0000313|EMBL:EJJ03086.1};
OS Streptomyces auratus AGR0001.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ03086.1};
RN [1] {ECO:0000313|EMBL:EJJ03086.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ03086.1};
RX PubMed=22965094; DOI=10.1128/JB.01155-12;
RA Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT Producing Actinomycete.";
RL J. Bacteriol. 194:5472-5473(2012).
RN [2] {ECO:0000313|EMBL:QTZ95935.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AGR0001 {ECO:0000313|EMBL:QTZ95935.1};
RA Wen M.-L., Han X.-L., Xiong J.;
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AJGV01000190; EJJ03086.1; -; Genomic_DNA.
DR EMBL; CP072931; QTZ95935.1; -; Genomic_DNA.
DR RefSeq; WP_006607599.1; NZ_CP072931.1.
DR AlphaFoldDB; J1ZNL2; -.
DR STRING; 1160718.SU9_30494; -.
DR KEGG; sauh:SU9_005895; -.
DR PATRIC; fig|1160718.3.peg.6163; -.
DR eggNOG; COG0258; Bacteria.
DR HOGENOM; CLU_004675_1_3_11; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000009036; Chromosome.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:EJJ03086.1};
KW Hydrolase {ECO:0000313|EMBL:EJJ03086.1};
KW Nuclease {ECO:0000313|EMBL:EJJ03086.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009036}.
FT DOMAIN 1..274
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 304 AA; 32339 MW; A012DDF9F7E96934 CRC64;
MLLDTASLYF RAYFGVPDSV RAPDGTPVNA VRGLLDFIAR LVQDHHPDDL VACMDFDWRP
QWRVDLIPSY KAHRVAEEAP AGSAEPDEEE IPDTLSPQVP VIEDVLDALG IARIGAAGYE
ADDVIGTLTA RAKGPVDIVT GDRDLFQLVD DRRGIRILYP LKGVGTLQVT DEALLRAKYG
VDGPGYADLA LLRGDPSDGL PGVPGIGEKT AAKLLDAYGD LAGILAAAAD PASKVTPAQR
TRLLEAGPYL AVAPKVVKVA TDVPVPAVDH TLPAEPADPE RLEALAAQWG LGGALQRLLV
TLRR
//
